Literature DB >> 1368098

Responsive polymer systems for controlled delivery of therapeutics.

J Kost1, R Langer.   

Abstract

The ideal drug-delivery system should provide therapeutics in response to physiological requirements, having the capacity to 'sense' changes and alter the drug-release process accordingly. Such responsive controlled delivery systems are still at an experimental stage. This review focuses on two basic approaches: (1) externally regulated systems (utilizing triggers such as magnetism, ultrasound, temperature and electricity), and (2) self-regulated systems (utilizing pH-sensitive polymers, enzyme-substrate reactions, competitive binding, and antibody interactions).

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Year:  1992        PMID： 1368098     DOI： 10.1016/0167-7799(92)90194-z

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN： 0167-7799            Impact factor:   19.536


  10 in total

1.  Calcium responsive bioerodible drug delivery system.

Authors:  R Goldbart; J Kost
Journal:  Pharm Res       Date:  1999-09       Impact factor: 4.200

Review 2.  Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release.

Authors:  Nazila Kamaly; Basit Yameen; Jun Wu; Omid C Farokhzad
Journal:  Chem Rev       Date:  2016-02-08       Impact factor: 60.622

Review 3.  Glucose-Responsive Insulin and Delivery Systems: Innovation and Translation.

Authors:  Jinqiang Wang; Zejun Wang; Jicheng Yu; Anna R Kahkoska; John B Buse; Zhen Gu
Journal:  Adv Mater       Date:  2019-08-18       Impact factor: 30.849

4.  Rational design of a dual-mode optical and chemical prodrug.

Authors:  Colin P McCoy; Clare Rooney; David S Jones; Sean P Gorman; Mark Nieuwenhuyzen
Journal:  Pharm Res       Date:  2006-11-16       Impact factor: 4.200

5.  Following Polymer Degradation with Nanodiamond Magnetometry.

Authors:  Runrun Li; Thea Vedelaar; Aldona Mzyk; Aryan Morita; Sandeep Kumar Padamati; Romana Schirhagl
Journal:  ACS Sens       Date:  2022-01-04       Impact factor: 7.711

Review 6.  Applications of polymeric smart materials to environmental problems.

Authors:  H N Gray; D E Bergbreiter
Journal:  Environ Health Perspect       Date:  1997-02       Impact factor: 9.031

7.  Drug delivery interfaces in the 21st century: from science fiction ideas to viable technologies.

Authors:  Beata Chertok; Matthew J Webber; Marc D Succi; Robert Langer
Journal:  Mol Pharm       Date:  2013-08-26       Impact factor: 4.939

Review 8.  Materials for diabetes therapeutics.

Authors:  Kaitlin M Bratlie; Roger L York; Michael A Invernale; Robert Langer; Daniel G Anderson
Journal:  Adv Healthc Mater       Date:  2012-04-05       Impact factor: 9.933

9.  Controlled delivery of zoledronate improved bone formation locally in vivo.

Authors:  Wenlong Gou; Xin Wang; Jiang Peng; Qiang Lu; Yu Wang; Aiyuan Wang; Quanyi Guo; Xupeng Gao; Wenjing Xu; Shibi Lu
Journal:  PLoS One       Date:  2014-03-11       Impact factor: 3.240

10.  Synthesis of an insulin intercalated graphene oxide nanogel composite: evaluation of its release profile and stability for oral delivery of insulin.

Authors:  Shabana Gul Baloch; Huma Shaikh; Shahnila Shah; Shahabuddin Memon; Ayaz Ali Memon
Journal:  Nanoscale Adv       Date:  2022-04-06
  10 in total

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