Literature DB >> 13678476

Anaemia in patients with diabetes: unrecognised, undetected and untreated?

Paul E Stevens1, Donal J O'Donoghue, Norbert R Lameire.   

Abstract

BACKGROUND: Diabetes mellitus is one of the two most common causes of end-stage renal disease and significant proportions of patients with diabetes mellitus develop renal complications. Anaemia is a key indicator of renal disease yet most patients with diabetes are rarely tested for anaemia and are unaware of the link between anaemia and kidney disease. PATIENTS AND METHODS: A pan-European study was undertaken to assess patients' level of awareness and understanding of anaemia and of the complications of diabetes mellitus, and to determine the impact of anaemia on quality of life. The study comprised a questionnaire-based interview with 1,054 respondents from six countries (Belgium, France, Germany, Greece, Italy and the UK). Ages ranged from 18 to 85, the average duration of diabetes was 15 years and 69% of respondents had type 2 diabetes mellitus.
RESULTS: Only 32% of respondents had been given information about anaemia, although 83% had heard of anaemia. Less than half were aware of being tested for anaemia and only 14% attributed anaemia to diabetes. Of 1,054 respondents, 132 were known to be anaemic, one-fifth had received no treatment, 12 had received blood transfusions, five were receiving erythropoietin therapy and the remainder had been given iron and/or vitamin supplementation. Perceived state of health was worse in those with anaemia, 47% had either experienced periods of ill health or were feeling in poor health generally compared with only 28% of those without anaemia. Tiredness and lethargy were more marked in those with anaemia, 74% feeling tired and lethargic considerably more often or somewhat more often than others compared with only 52% of those without anaemia. With respect to complications of diabetes, respondents were most concerned about retinopathy (40%) but 23% were concerned about developing nephropathy. Only 46% had received information about renal complications.
CONCLUSIONS: Anaemia has a significant impact on the quality of life of patients with diabetes. Although patients are aware of anaemia, their awareness of being tested for anaemia is low. A significant number of those in whom anaemia was detected received no treatment. It is likely that anaemia in patients with diabetes is unrecognised, undetected and untreated.

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Year:  2003        PMID: 13678476     DOI: 10.1185/030079903125002036

Source DB:  PubMed          Journal:  Curr Med Res Opin        ISSN: 0300-7995            Impact factor:   2.580


  10 in total

Review 1.  Anemia and diabetic nephropathy.

Authors:  Eberhard Ritz
Journal:  Curr Diab Rep       Date:  2006-12       Impact factor: 4.810

Review 2.  Anemia and cardiovascular disease in diabetic nephropathy.

Authors:  Samy I McFarlane; Moro O Salifu; John Makaryus; James R Sowers
Journal:  Curr Diab Rep       Date:  2006-06       Impact factor: 4.810

Review 3.  Anaemia in diabetes: Is there a rationale to TREAT?

Authors:  M C Thomas; M E Cooper; K Rossing; H H Parving
Journal:  Diabetologia       Date:  2006-04-04       Impact factor: 10.122

4.  The Relationship between Anemia and the Initiation of Dialysis in Patients with Type 2 Diabetic Nephropathy.

Authors:  Sun Hee Kim; Kyung Ae Lee; Heung Yong Jin; Hong Sun Baek; Tae Sun Park
Journal:  Diabetes Metab J       Date:  2015-04-22       Impact factor: 5.376

5.  Presence and characterisation of anaemia in diabetic foot ulceration.

Authors:  J A Wright; M J Oddy; T Richards
Journal:  Anemia       Date:  2014-07-23

6.  Anemia in patients with diabetic foot ulcer and its impact on disease outcome among Nigerians: Results from the MEDFUN study.

Authors:  Ibrahim D Gezawa; Ejiofor T Ugwu; Ignatius Ezeani; Olufunmilayo Adeleye; Innocent Okpe; Marcelina Enamino
Journal:  PLoS One       Date:  2019-12-17       Impact factor: 3.240

7.  Magnitude and factors associated with anemia among diabetic patients in Ethiopia: A systematic review and meta-analysis.

Authors:  Daniel Atlaw; Zerihun Tariku
Journal:  SAGE Open Med       Date:  2021-07-09

8.  A case-control study of prevalence of anemia among patients with type 2 diabetes.

Authors:  Samuel Antwi-Bafour; Samuel Hammond; Jonathan Kofi Adjei; Ransford Kyeremeh; Alexander Martin-Odoom; Ivy Ekem
Journal:  J Med Case Rep       Date:  2016-05-04

9.  Anemia in type 2 diabetic patients and correlation with kidney function in a tertiary care sub-Saharan African hospital: a cross-sectional study.

Authors:  Vitalis F Feteh; Simeon-Pierre Choukem; Andre-Pascal Kengne; Daniel N Nebongo; Marcelin Ngowe-Ngowe
Journal:  BMC Nephrol       Date:  2016-03-19       Impact factor: 2.388

10.  Prevalence of anemia in diabetic adult outpatients in Northeast Ethiopia.

Authors:  Temesgen Fiseha; Aderaw Adamu; Melkam Tesfaye; Angesom Gebreweld
Journal:  PLoS One       Date:  2019-09-09       Impact factor: 3.240

  10 in total

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