Literature DB >> 1367716

Streptomyces: a host for heterologous gene expression.

M Brawner1, G Poste, M Rosenberg, J Westpheling.   

Abstract

Streptomyces species offer many potential advantages as hosts for the expression and secretion of eukaryotic gene products. In this review we discuss the expression and localization signals that have been used to direct heterologous gene expression and the applications of these signals. Finally, we discuss future strategies aimed at increasing the capacity of this host for the high level production of biologically active eukaryotic gene products.

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Year:  1991        PMID： 1367716     DOI： 10.1016/0958-1669(91)90033-2

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  8 in total

Review 1.  Engineering of a genome-reduced host: practical application of synthetic biology in the overproduction of desired secondary metabolites.

Authors:  Hong Gao; Ying Zhuo; Elizabeth Ashforth; Lixin Zhang
Journal:  Protein Cell       Date:  2010-07-29       Impact factor: 14.870

2.  Isolation and characterization of two genes encoding proteases associated with the mycelium of Streptomyces lividans 66.

Authors:  C Binnie; M J Butler; J S Aphale; R Bourgault; M A DiZonno; P Krygsman; L Liao; E Walczyk; L T Malek
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490

3.  Cloning and analysis of a gene from Streptomyces lividans 66 encoding a novel secreted protease exhibiting homology to subtilisin BPN'.

Authors:  M J Butler; J S Aphale; C Binnie; M A DiZonno; P Krygsman; G Soltes; E Walczyk; L T Malek
Journal:  Appl Microbiol Biotechnol       Date:  1996-03       Impact factor: 4.813

4.  Streptomyces lividans glycosylates the linker region of a beta-1,4-glycanase from Cellulomonas fimi.

Authors:  E Ong; D G Kilburn; R C Miller; R A Warren
Journal:  J Bacteriol       Date:  1994-02       Impact factor: 3.490

5.  The SmpB-tmRNA tagging system plays important roles in Streptomyces coelicolor growth and development.

Authors:  Chunzhong Yang; John R Glover
Journal:  PLoS One       Date:  2009-02-12       Impact factor: 3.240

Review 6.  Reviewing a plethora of oxidative-type reactions catalyzed by whole cells of Streptomyces species.

Authors:  Sara Salama; Mohamed H Habib; Rajni Hatti-Kaul; Yasser Gaber
Journal:  RSC Adv       Date:  2022-03-01       Impact factor: 3.361

7.  Metabolomics investigation of recombinant mTNFα production in Streptomyces lividans.

Authors:  Howbeer Muhamadali; Yun Xu; David I Ellis; Drupad K Trivedi; Nicholas J W Rattray; Kristel Bernaerts; Royston Goodacre
Journal:  Microb Cell Fact       Date:  2015-10-09       Impact factor: 5.328

8.  Effects of Nonstarch Genetic Modifications on Starch Structure and Properties.

Authors:  Shiyao Yu; Dengxiang Du; Alex C Wu; Yeming Bai; Peng Wu; Cheng Li; Robert G Gilbert
Journal:  Foods       Date:  2020-02-20
  8 in total

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