| Literature DB >> 1367187 |
N Danhash1, D C Gardner, S G Oliver.
Abstract
The introduction of plasmid DNA into yeast by transformation or electroporation, but not by cytoduction, results in the induction of a slow growth phenotype. This phenotype is inherited as a dominant Mendelian trait, which is only exhibited in the absence of the native 2 mu nuclear DNA plasmid of yeast. The use of recombinant DNA technology in yeast, therefore, does not necessarily manipulate the genome in a precise and completely defined way.Entities:
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Year: 1991 PMID： 1367187 DOI： 10.1038/nbt0291-179
Source DB: PubMed Journal: Biotechnology (N Y) ISSN： 0733-222X