Literature DB >> 1362558

Linkage to Xq28 in a family with nonspecific X-linked mental retardation.

A M Nordström1, M Penttinen, H von Koskull.   

Abstract

Linkage analysis was performed in a family with nonspecific X-linked mental retardation (MRX). Affected individuals had no clinical characteristics other than mental retardation. Linkage was detected to the marker loci DXS477, DXS465, DXS52, DXS15 and F8C with maximum lod scores of 1.70, 1.32, 2.52, 1.70, and 1.09, respectively (theta = 0.0). The results strongly indicate that the gene for mental retardation in the family studied maps close to DXS52.

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Year:  1992        PMID： 1362558     DOI： 10.1007/bf00220075

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  16 in total

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2.  Four chromosomal breakpoints and four new probes mark out a 10-cM region encompassing the fragile-X locus (FRAXA).

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Journal:  Am J Hum Genet       Date:  1991-01       Impact factor: 11.025

3.  The telomeric region of the human X chromosome long arm: presence of a highly polymorphic DNA marker and analysis of recombination frequency.

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Journal:  Hum Genet       Date:  1989-07       Impact factor: 4.132

5.  Improved DNA markers for efficient analysis of fragile X families.

Authors:  R Heilig; I Oberlé; B Arveiler; A Hanauer; M Vidaud; J L Mandel
Journal:  Am J Med Genet       Date:  1988 May-Jun

6.  Physical fine mapping of the choroideremia locus using Xq21 deletions associated with complex syndromes.

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Journal:  Genomics       Date:  1989-01       Impact factor: 5.736

7.  Genetic mapping and diagnosis of haemophilia A achieved through a BclI polymorphism in the factor VIII gene.

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Journal:  Nature       Date:  1985 Apr 25-May 1       Impact factor: 49.962

8.  A clinically useful DNA probe closely linked to haemophilia A.

Authors:  K Harper; R M Winter; M E Pembrey; D Hartley; K E Davies; E G Tuddenham
Journal:  Lancet       Date:  1984-07-07       Impact factor: 79.321

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Authors:  G M Lathrop; J M Lalouel; C Julier; J Ott
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

10.  Linkage studies of X-linked recessive spastic paraplegia using DNA probes.

Authors:  S Kenwrick; V Ionasescu; G Ionasescu; C Searby; A King; M Dubowitz; K E Davies
Journal:  Hum Genet       Date:  1986-07       Impact factor: 4.132
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  7 in total

1.  A new X linked recessive syndrome of mental retardation and mild dysmorphism maps to Xq28.

Authors:  G S Pai; B Hane; M Joseph; R Nelson; L S Hammond; J F Arena; H A Lubs; R E Stevenson; C E Schwartz
Journal:  J Med Genet       Date:  1997-07       Impact factor: 6.318

2.  PPM-X: a new X-linked mental retardation syndrome with psychosis, pyramidal signs, and macroorchidism maps to Xq28.

Authors:  S Lindsay; M Splitt; S Edney; T P Berney; S J Knight; K E Davies; O O'Brien; M Gale; J Burn
Journal:  Am J Hum Genet       Date:  1996-06       Impact factor: 11.025

3.  A gene for dominant nonspecific X-linked mental retardation is located in Xq28.

Authors:  V des Portes; P Billuart; A Carrié; L Bachner; T Bienvenu; M C Vinet; C Beldjord; G Ponsot; A Kahn; J Boué; J Chelly
Journal:  Am J Hum Genet       Date:  1997-04       Impact factor: 11.025

4.  Identification of a 650 kb duplication at the X chromosome breakpoint in a patient with 46,X,t(X;8)(q28;q12) and non-syndromic mental retardation.

Authors:  J J Cox; S T Holden; S Dee; J I Burbridge; F L Raymond
Journal:  J Med Genet       Date:  2003-03       Impact factor: 6.318

5.  Homosexuality, type 1: an Xq28 phenomenon.

Authors:  W J Turner
Journal:  Arch Sex Behav       Date:  1995-04

6.  X-linked mental retardation: in pursuit of a gene map.

Authors:  C E Schwartz
Journal:  Am J Hum Genet       Date:  1993-06       Impact factor: 11.025

7.  Molecular cloning and characterization of a novel mouse actin-binding protein Zfp185.

Authors:  Na Wang; Quanhui Zheng; Jin-San Zhang; Yong Zhao
Journal:  J Mol Histol       Date:  2008-02-01       Impact factor: 2.611
  7 in total

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