| Literature DB >> 1355471 |
T Aoyagi1, M Hatsu, F Kojima, C Hayashi, M Hamada, T Takeuchi.
Abstract
We found benarthin, a new inhibitor of pyroglutamyl peptidase, in the fermentation broth of Streptomyces xanthophaeus MJ244-SF1. It was purified by column chromatography and centrifugal partition chromatography (CPC) and then was isolated as a colorless powder. The binding of benarthin was competitive with substrate and its inhibition constant (Ki) was 1.2 x 10(-6) M.Entities:
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Year: 1992 PMID： 1355471 DOI： 10.7164/antibiotics.45.1079
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649