Literature DB >> 1353461

NO., CO and .OH. Endogenous soluble guanylyl cyclase-activating factors.

H H Schmidt1.   

Abstract

Several low molecular weight compounds are capable of activating soluble guanylyl cyclase. Recent evidence suggests that some of these are formed under physiological conditions: the nitric oxide radical, carbon monoxide and the hydroxyl radical. Thus, multiple signal transduction pathways appear to exist that form a family of guanylyl cyclase activating factors and thereby regulate the intracellular cyclic guanosine 3',5'-monophosphate level.

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Year:  1992        PMID: 1353461     DOI: 10.1016/0014-5793(92)80910-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  26 in total

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4.  Heme oxygenase-1 is a potent inhibitor of placental ischemia-mediated endothelin-1 production in cultured human glomerular endothelial cells.

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5.  Gastric motility in soluble guanylate cyclase alpha 1 knock-out mice.

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6.  The adventitia may be a barrier specific to nitric oxide in rabbit pulmonary artery.

Authors:  R H Steinhorn; F C Morin; J A Russell
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7.  Inhibition by zinc protoporphyrin-IX of receptor-mediated relaxation of the rat aorta in a manner distinct from inhibition of haem oxygenase.

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8.  Hydrogen peroxide at low concentrations strongly enhances the inhibitory effect of nitric oxide on platelets.

Authors:  K M Naseem; K R Bruckdorfer
Journal:  Biochem J       Date:  1995-08-15       Impact factor: 3.857

Review 9.  Pathogenesis of malaria and clinically similar conditions.

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10.  YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase.

Authors:  C C Wu; F N Ko; S C Kuo; F Y Lee; C M Teng
Journal:  Br J Pharmacol       Date:  1995-10       Impact factor: 8.739

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