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Literature DB >> 1353064

Expression of interleukin-6 receptor on blood lymphocytes without in vitro activation.

Abstract

A monoclonal antibody against the interleukin-6 receptor (IL-6R) has been used in a high-sensitivity immunofluorescence technique to study receptor expression on unstimulated blood lymphocytes. Most CD4 cells express IL-6 receptor, whilst a small and variable proportion of CD8 and B cells are positive. CD4+ cells express higher levels of receptor than CD8+ T cells, and CD45RO+ cells express higher levels than CD45RA cells.

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Year: 1992 PMID： 1353064 PMCID： PMC1421523

Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397

10 in total

1. Characterization of IL-6 receptor expression by monoclonal and polyclonal antibodies.

Authors: Y Hirata; T Taga; M Hibi; N Nakano; T Hirano; T Kishimoto
Journal: J Immunol Date: 1989-11-01 Impact factor: 5.422

2. Detection by immunofluorescence of surface molecules present in low copy numbers. High sensitivity staining and calibration of flow cytometer.

Authors: H Zola; S H Neoh; B X Mantzioris; J Webster; M S Loughnan
Journal: J Immunol Methods Date: 1990-12-31 Impact factor: 2.303

3. Circulating human T and B lymphocytes express the p55 interleukin-2 receptor molecule (TAC, CD25).

Authors: H Zola; B X Mantzioris; J Webster; F E Kette
Journal: Immunol Cell Biol Date: 1989-08 Impact factor: 5.126

Review 4. The biology of interleukin-6.

Authors: T Kishimoto
Journal: Blood Date: 1989-07 Impact factor: 22.113

5. Distinct roles of IL-1 and IL-6 in human T cell activation.

Authors: F A Houssiau; P G Coulie; J Van Snick
Journal: J Immunol Date: 1989-10-15 Impact factor: 5.422

6. Enhancement of the interleukin 2 receptor expression on T cells by multiple B-lymphotropic lymphokines.

Authors: T Noma; T Mizuta; A Rosén; T Hirano; T Kishimoto; T Honjo
Journal: Immunol Lett Date: 1987-07 Impact factor: 3.685

7. A monoclonal antibody 7G7/B6, binds to an epitope on the human interleukin-2 (IL-2) receptor that is distinct from that recognized by IL-2 or anti-Tac.

Authors: L A Rubin; C C Kurman; W E Biddison; N D Goldman; D L Nelson
Journal: Hybridoma Date: 1985

8. Expression of the p70 chain of the IL-2 receptor on human lymphoid cells: analysis using a monoclonal antibody and high-sensitivity immunofluorescence.

Authors: H Zola; R J Purling; L Y Koh; M Tsudo
Journal: Immunol Cell Biol Date: 1990-08 Impact factor: 5.126

9. Infection with HIV is associated with elevated IL-6 levels and production.

Authors: E C Breen; A R Rezai; K Nakajima; G N Beall; R T Mitsuyasu; T Hirano; T Kishimoto; O Martinez-Maza
Journal: J Immunol Date: 1990-01-15 Impact factor: 5.422

10. Receptors for B cell stimulatory factor 2. Quantitation, specificity, distribution, and regulation of their expression.

Authors: T Taga; Y Kawanishi; R R Hardy; T Hirano; T Kishimoto
Journal: J Exp Med Date: 1987-10-01 Impact factor: 14.307

10 in total

5 in total

1. Transcriptional network profile on synovial fluid T cells in psoriatic arthritis.

Authors: Ugo Fiocco; Veronica Martini; Benedetta Accordi; Francesco Caso; Luisa Costa; Francesca Oliviero; Anna Scanu; Monica Facco; Daniele Boso; Mariele Gatto; Mara Felicetti; Paola Frallonardo; Roberta Ramonda; Lucia Piva; Renato Zambello; Carlo Agostini; Raffaele Scarpa; Giuseppe Basso; Gianpietro Semenzato; Jean-Michel Dayer; Leonardo Punzi; Andrea Doria
Journal: Clin Rheumatol Date: 2015-07-09 Impact factor: 2.980