| Literature DB >> 1352704 |
Y Misumi1, Y Hayashi, F Arakawa, Y Ikehara.
Abstract
The cDNA coding for the human dipeptidyl peptidase IV (DPPIV) has been isolated and sequenced. The nucleotide sequence (3465 bp) of the cDNA contains an open reading frame encoding a polypeptide comprising 766 amino acids, one residue less than those of rat DPPIV. The predicted amino acid sequence exhibits 84.9% identity to that of the rat enzyme, and contains nine potential N-linked glycosylation sites, one site more than those in the rat enzyme. A putative catalytic triad for serine proteinases, serine, aspartic acid and histidine, are found in a completely conserved COOH-terminal region (positions 625-752).Entities:
Mesh：
Substances：
Year: 1992 PMID： 1352704 DOI： 10.1016/0167-4781(92)90036-y
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002