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Literature DB >> 1350385

Mechanism of action of taxol.

S B Horwitz¹.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 1992 PMID： 1350385 DOI： 10.1016/0165-6147(92)90048-b

Source DB: PubMed Journal: Trends Pharmacol Sci ISSN： 0165-6147 Impact factor: 14.819

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113 in total

1. Design and synthesis of simplified taxol analogs based on the T-Taxol bioactive conformation.

Authors: Jielu Zhao; Susan Bane; James P Snyder; Haipeng Hu; Kamalika Mukherjee; Carla Slebodnick; David G I Kingston
Journal: Bioorg Med Chem Date: 2011-10-13 Impact factor: 3.641

Review 2. Mechanisms of Taxol resistance related to microtubules.

Authors: George A Orr; Pascal Verdier-Pinard; Hayley McDaid; Susan Band Horwitz
Journal: Oncogene Date: 2003-10-20 Impact factor: 9.867

3. Microtubule bundling and nested buckling drive stripe formation in polymerizing tubulin solutions.

Authors: Yifeng Liu; Yongxing Guo; James M Valles; Jay X Tang
Journal: Proc Natl Acad Sci U S A Date: 2006-07-03 Impact factor: 11.205

4. Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3' bridged paclitaxel analogues.

Authors: Thota Ganesh; Chao Yang; Andrew Norris; Tom Glass; Susan Bane; Rudravajhala Ravindra; Abhijit Banerjee; Belhu Metaferia; Shala L Thomas; Paraskevi Giannakakou; Ana A Alcaraz; Ami S Lakdawala; James P Snyder; David G I Kingston
Journal: J Med Chem Date: 2007-01-31 Impact factor: 7.446

Mechanism of action of taxol.

1. Design and synthesis of simplified taxol analogs based on the T-Taxol bioactive conformation.

Review 2. Mechanisms of Taxol resistance related to microtubules.

3. Microtubule bundling and nested buckling drive stripe formation in polymerizing tubulin solutions.

4. Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3' bridged paclitaxel analogues.

5. Cisplatinum and taxol induce different patterns of p53 phosphorylation.

6. Induction of paclitaxel resistance by the Kaposi's sarcoma-associated herpesvirus latent protein LANA2.

7. Chemotherapy in Androgen-Independent Prostate Cancer (AIPC): What's next after taxane progression?

8. Alternol inhibits proliferation and induces apoptosis in mouse lymphocyte leukemia (L1210) cells.

Review 9. A preliminary risk-benefit assessment of paclitaxel.

10. Analysis of HGF, MACC1, C-met and apoptosis-related genes in cervical carcinoma mice.