Literature DB >> 1350294

Structure of the mouse IL-10 gene and chromosomal localization of the mouse and human genes.

J M Kim1, C I Brannan, N G Copeland, N A Jenkins, T A Khan, K W Moore.   

Abstract

The nucleotide sequence of a 7.2-kb segment containing the mouse IL-10 (mIL-10) gene was determined. Comparison to the mIL-10 cDNA sequence (Moore, K. W., et al. 1990. Science 248:1230; 250:494) revealed the presence of five exons that span approximately 5.1 kb of genomic DNA. The noncoding regions of the mIL-10 gene contain sequences that have been associated with transcriptional regulation of several cytokine genes. The mIL-10 gene was mapped to mouse chromosome 1 and the human IL-10 gene was also mapped to human chromosome 1.

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Year:  1992        PMID： 1350294

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  41 in total

1.  Genetic restriction of HIV-1 pathogenesis to AIDS by promoter alleles of IL10.

Authors:  H D Shin; C Winkler; J C Stephens; J Bream; H Young; J J Goedert; T R O'Brien; D Vlahov; S Buchbinder; J Giorgi; C Rinaldo; S Donfield; A Willoughby; S J O'Brien; M W Smith
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

2.  Activation of the IL-10 gene promoter following photodynamic therapy of murine keratinocytes.

Authors:  S O Gollnick; B Y Lee; L Vaughan; B Owczarczak; B W Henderson
Journal:  Photochem Photobiol       Date:  2001-02       Impact factor: 3.421

3.  Epstein-Barr virus recombinants with specifically mutated BCRF1 genes.

Authors:  S Swaminathan; R Hesselton; J Sullivan; E Kieff
Journal:  J Virol       Date:  1993-12       Impact factor: 5.103

4.  Mapping of eight human chromosome 1 orthologs to cattle chromosomes 3 and 16.

Authors:  J E Beever; S R Fisher; G Guérin; H A Lewin
Journal:  Mamm Genome       Date:  1997-07       Impact factor: 2.957

5.  Interferon gamma and Interleukin 10 polymorphisms in Brazilian patients with systemic lupus erythematosus.

Authors:  Hildson Dornelas Angelo da Silva; Alex Paulino da Silva; Helker Albuquerque da Silva; Nadja Maria Jorge Asano; Maria de Mascena Diniz Maia; Paulo Roberto Eleutério de Souza
Journal:  Mol Biol Rep       Date:  2014-01-18       Impact factor: 2.316

6.  Association of interleukin-10 gene polymorphisms with breast cancer in a Chinese population.

Authors:  Fanjun Kong; Jie Liu; Yongheng Liu; Bao Song; Hualing Wang; Wenchao Liu
Journal:  J Exp Clin Cancer Res       Date:  2010-06-17

7.  Intereleukin-10 promoter polymorphism in mild cognitive impairment and in its clinical evolution.

Authors:  Beatrice Arosio; Luigina Mastronardi; Carlo Vergani; Giorgio Annoni
Journal:  Int J Alzheimers Dis       Date:  2010-07-20

8.  Interleukin 10 gene promoter polymorphisms in women with early-onset pre-eclampsia.

Authors:  S Sowmya; K Sri Manjari; A Ramaiah; T Sunitha; P Nallari; A Jyothy; A Venkateshwari
Journal:  Clin Exp Immunol       Date:  2014-11       Impact factor: 4.330

9.  Disruption in the AU motif of the mouse TNF-alpha 3' UTR correlates with reduced TNF production by macrophages in vitro.

Authors:  C O Jacob; N B Tashman
Journal:  Nucleic Acids Res       Date:  1993-06-11       Impact factor: 16.971

10.  Activation and proliferation signals in primary human T lymphocytes inhibited by ergosterol peroxide isolated from Cordyceps cicadae.

Authors:  Y C Kuo; S C Weng; C J Chou; T T Chang; W J Tsai
Journal:  Br J Pharmacol       Date:  2003-09-22       Impact factor: 8.739
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