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Literature DB >> 13475606

Macroglobulinemia. I. The antigenic relationship of pathological macroglobulins to normal gamma-globulins.

Abstract

Highly purified pathological macroglobulins, which had been characterized electrophoretically and in the ultracentrifuge, were studied by the Ouchterlony gel diffusion technique. These macroglobulins were shown to be antigenically related to normal gamma(1)-macroglobulin (19S) as well as the 7S gamma-globulins. The pathological macroglobulins differ among each other and they are antigenically deficient when compared with the normal macroglobulin. There is no correlation between the macroglobulin's antigenic structure and its physico-chemical properties.

Entities: Disease

Keywords: GAMMA GLOBULIN; SERUM GLOBULIN

Mesh：

Substances：

Year: 1957 PMID： 13475606 PMCID： PMC2136814 DOI： 10.1084/jem.106.4.467

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

18 in total

7. TWO TYPES OF gamma-MYELOMA PROTEINS, beta(2A)-MYELOMA PROTEINS, gamma(1)-MACROGLOBULINS, AND BENCE JONES PROTEINS IDENTIFIED BY TWO GROUPS OF COMMON ANTIGENIC DETERMINANTS.

Authors: J L Fahey; A Solomon
Journal: J Clin Invest Date: 1963-06 Impact factor: 14.808

8. [The optical rotation dispersion of isolated parapro- teins. II. On group specificity of pathologic gammaM proteins].

Authors: O Wetter; K Janke; C Hertenstein
Journal: Klin Wochenschr Date: 1966-05-15

9. Immunofluorescent localization of immunoglobulins, complement, and fibrinogen in human diseases. I. Systemic lupus erythematosus.

Authors: F Paronetto; D Koffler
Journal: J Clin Invest Date: 1965-10 Impact factor: 14.808

10. Macroglobulinemia. III. The effect of mercaptoethanol on the antigenic structure of macroglobulins.

Authors: L KORNGOLD; G VAN LEEUWEN
Journal: J Exp Med Date: 1959-07-01 Impact factor: 14.307

Macroglobulinemia. I. The antigenic relationship of pathological macroglobulins to normal gamma-globulins.

1. Tissue antigens of human tumors grown in rats, hamsters, and eggs.

2. The effect of the antigen's molecular weight on the curvature of the precipitin line in the Ouchterlony technic.

3. Antigenic identity of hyperglobulinemic serum components with proteins of normal serum.

4. A crystalline macroglobulin from human serum.

5. Two types of gamma-globulin differing in carbohydrate content.

6. Immunological cross-reactions studied by the Ouchterlony gel diffusion technique; theory and practice.

7. [Antigen analysis of paraprotein in macroglobulinemia].

8. Abnormal proteins in myeloma.

9. An unusual case of hyperglobulinaemia.

10. The carbohydrate of gamma-globulin and myeloma proteins.

1. CHROMOSOMES AND SERUM PROTEINS: A LINKED ABNORMALITY.

2. [INCIDENCE AND CLINICAL SIGNIFICANCE OF PARAPROTEINEMIA].

3. IMMUNOCYTOCHEMICAL OBSERVATIONS ON THE VASCULAR NECROSIS AND RENAL GLOMERULAR LESIONS OF MALIGNANT NEPHROSCLEROSIS.

4. Acquired tolerance, autoantibodies and cancer.

5. Macroglobulinaemia with cryoglobulinaemia in a case of acquired syphilis.

6. Studies on the isolation and characterization of the "rheumatoid factor".

7. TWO TYPES OF gamma-MYELOMA PROTEINS, beta(2A)-MYELOMA PROTEINS, gamma(1)-MACROGLOBULINS, AND BENCE JONES PROTEINS IDENTIFIED BY TWO GROUPS OF COMMON ANTIGENIC DETERMINANTS.

8. [The optical rotation dispersion of isolated parapro- teins. II. On group specificity of pathologic gammaM proteins].

9. Immunofluorescent localization of immunoglobulins, complement, and fibrinogen in human diseases. I. Systemic lupus erythematosus.

10. Macroglobulinemia. III. The effect of mercaptoethanol on the antigenic structure of macroglobulins.