Literature DB >> 13460237

The enzymatic hydrolysis of imidazoleacryloylcholine (murexine) and imidazolepropionylcholine (dihydromurexine) by various cholinesterases.

M E GRELIS, I I TABACHNICK.   

Abstract

Several choline esters, including the imidazoleacryloyl and imidazolepropionyl compounds, have been hydrolysed by cholinesterases from various sources. The imidazolepropionyl ester was metabolized by cholinesterases obtained from human plasma, ox spleen, ox serum, and guinea-pig liver, but not by rat liver or bovine red cell cholinesterase. It is suggested the imidazolepropionylcholine or a closely related ester might be the natural substrate for "non-specific" cholinesterase.

Entities:  

Keywords:  CHOLINE/related compounds; CHOLINESTERASE/effects

Mesh:

Substances:

Year:  1957        PMID: 13460237      PMCID: PMC1509698          DOI: 10.1111/j.1476-5381.1957.tb00141.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN: 0366-0826


  6 in total

1.  Interrelationship of murexine, dihydromurexine and human cholinesterases.

Authors:  F F FOLDES; E G ERDOS; N BAART; S P SHANOR
Journal:  Proc Soc Exp Biol Med       Date:  1957-03

2.  The actual nitrogen sources for growth of heterotrophic bacteria in non-limiting media.

Authors:  A C WARNER
Journal:  Biochem J       Date:  1956-09       Impact factor: 3.857

3.  Identification of pseudocholinesterase in the tissues of ruminants.

Authors:  B MENDEL; D K MYERS
Journal:  Nature       Date:  1955-10-22       Impact factor: 49.962

4.  Identification of murexine as beta-(imidazolyl-(4))-acrylcholine.

Authors:  V ERSPAMER; O BENATI
Journal:  Science       Date:  1953-02-13       Impact factor: 47.728

5.  The occurrence of homologues of acetylcholine in ox spleen.

Authors:  J BANISTER; V P WHITTAKER; S WIJESUNDERA
Journal:  J Physiol       Date:  1953-07       Impact factor: 5.182

6.  HYDROLYSIS OF CHOLINE ESTERS BY LIVER.

Authors:  C H Sawyer
Journal:  Science       Date:  1945-04-13       Impact factor: 47.728

  6 in total
  2 in total

1.  Some pharmacological properties of murexine (urocanoylcholine).

Authors:  M J KEYL; V P WHITTAKER
Journal:  Br J Pharmacol Chemother       Date:  1958-03

2.  The pharmacological actions of some murexine-like substances.

Authors:  V ERSPAMER; A GLASSER
Journal:  Br J Pharmacol Chemother       Date:  1958-12
  2 in total

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