Literature DB >> 13446843

Structure-activity relationships observed on screening a series of pyrazolopyrimidines against experimental neoplasms.

H E SKIPPER, R K ROBINS, J R THOMSON, C C CHENG, R W BROCKMAN, F M SCHABEL.   

Abstract

Entities:  

Keywords:  CYTOTOXIC DRUGS

Mesh：

Substances：

Year:  1957        PMID： 13446843

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


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  4 in total

1.  4-Aminopyrazolo[3,4-d]pyrimidine (4-APP) as a novel inhibitor of the RNA and DNA depurination induced by Shiga toxin 1.

Authors:  M Brigotti; D Carnicelli; P Accorsi; S Rizzi; L Montanaro; S Sperti
Journal:  Nucleic Acids Res       Date:  2000-06-15       Impact factor: 16.971

2.  Docking Small Molecules to Predicted Off-Targets of the Cancer Drug Erlotinib Leads to Inhibitors of Lung Cancer Cell Proliferation with Suitable In vitro Pharmacokinetic Properties.

Authors:  Liwei Li; Jing Li; May Khanna; Inha Jo; Jason P Baird; Samy O Meroueh
Journal:  ACS Med Chem Lett       Date:  2010-08-12       Impact factor: 4.345

3.  Biological activity of analogs of guanine and guanosine against American Trypanosoma and Leishmania spp.

Authors:  J L Avila; T Rojas; A Avila; M A Polegre; R K Robins
Journal:  Antimicrob Agents Chemother       Date:  1987-03       Impact factor: 5.191

4.  Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells.

Authors:  Tokuhiro Chano; Sofia Avnet; Katsuyuki Kusuzaki; Gloria Bonuccelli; Pierre Sonveaux; Dante Rotili; Antonello Mai; Nicola Baldini
Journal:  Am J Cancer Res       Date:  2016-03-15       Impact factor: 6.166
  4 in total

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