| Literature DB >> 1336037 |
B Gulanowski1, J Swiatek, H Kozłowski.
Abstract
Chromatography on hydroxyapatite, polarography, and spectroscopy have been used to evaluate the interactions of Cr(III) and Cr(VI) with DNA and nucleoside triphosphates. Cr(III) catalyzes the removal of pyrophosphate from nucleoside triphosphate (NTP) molecules. It also causes extensive aggregations of DNA through DNA-DNA cross-linking. Cr(VI) does not affect the DNA structure unless reduced to lower oxidation states.Entities:
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Year: 1992 PMID: 1336037 DOI: 10.1016/0162-0134(92)84055-r
Source DB: PubMed Journal: J Inorg Biochem ISSN: 0162-0134 Impact factor: 4.155