| Literature DB >> 1335809 |
Abstract
Alu repeats are short interspersed elements whose transposition has lead to genetic variability and heritable disorders in humans. A select subset of the nearly one million Alu sequences in human DNA actually produce new transpositions. The evolution of newly inserted Alu repeats is currently a key subject for study. Mechanisms of RNA polymerase III activity and the sequence environment into which an Alu inserts might select for transcriptional and posttranscriptional determinants of Alu transposition.Entities:
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Year: 1992 PMID: 1335809 DOI: 10.1016/s0959-437x(05)80110-8
Source DB: PubMed Journal: Curr Opin Genet Dev ISSN: 0959-437X Impact factor: 5.578