Literature DB >> 1335624

Why is the genome variable? Insights from Drosophila.

C F Aquadro1.   

Abstract

The analysis of variation in DNA restriction maps and DNA sequence in natural populations of Drosophila melanogaster and related species has revealed a remarkable richness of diversity. This review describes some of the results of population genetic studies of this variation that are beginning to reveal how interactions between natural selection, genetic drift, mutation rate, recombination rate and population size have contributed to the observed patterns.

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Year:  1992        PMID： 1335624     DOI： 10.1016/0168-9525(92)90281-8

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  27 in total

1.  SNP profile within the human major histocompatibility complex reveals an extreme and interrupted level of nucleotide diversity.

Authors:  S Gaudieri; R L Dawkins; K Habara; J K Kulski; T Gojobori
Journal:  Genome Res       Date:  2000-10       Impact factor: 9.043

2.  DNA sequence polymorphism and divergence at the erect wing and suppressor of sable loci of Drosophila melanogaster and D. simulans.

Authors:  John M Braverman; Brian P Lazzaro; Montserrat Aguadé; Charles H Langley
Journal:  Genetics       Date:  2005-06-08       Impact factor: 4.562

3.  Sequencing multiple and diverse rice varieties. Connecting whole-genome variation with phenotypes.

Authors:  Kenneth L McNally; Richard Bruskiewich; David Mackill; C Robin Buell; Jan E Leach; Hei Leung
Journal:  Plant Physiol       Date:  2006-05       Impact factor: 8.340

4.  DNA variability and recombination rates at X-linked loci in humans.

Authors:  M W Nachman; V L Bauer; S L Crowell; C F Aquadro
Journal:  Genetics       Date:  1998-11       Impact factor: 4.562

5.  Gene conversion as a focusing mechanism for correlated mutations: a hypothesis.

Authors:  J Ninio
Journal:  Mol Gen Genet       Date:  1996-07-19

6.  Reduced variation in Drosophila simulans mitochondrial DNA.

Authors:  J W Ballard; J Hatzidakis; T L Karr; M Kreitman
Journal:  Genetics       Date:  1996-12       Impact factor: 4.562

7.  Large number of replacement polymorphisms in rapidly evolving genes of Drosophila. Implications for genome-wide surveys of DNA polymorphism.

Authors:  K J Schmid; L Nigro; C F Aquadro; D Tautz
Journal:  Genetics       Date:  1999-12       Impact factor: 4.562

8.  African Drosophila melanogaster and D. simulans populations have similar levels of sequence variability, suggesting comparable effective population sizes.

Authors:  Viola Nolte; Christian Schlötterer
Journal:  Genetics       Date:  2008-01       Impact factor: 4.562

9.  Mutational mechanisms, phylogeny, and evolution of a repetitive region within a clock gene of Drosophila melanogaster.

Authors:  E Rosato; A A Peixoto; A Gallippi; C P Kyriacou; R Costa
Journal:  J Mol Evol       Date:  1996-04       Impact factor: 2.395

10.  Inferring weak selection from patterns of polymorphism and divergence at "silent" sites in Drosophila DNA.

Authors:  H Akashi
Journal:  Genetics       Date:  1995-02       Impact factor: 4.562
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