| Literature DB >> 1335084 |
S A Baylis1, L K Dixon, S Vydelingum, G L Smith.
Abstract
Nucleotide sequencing of a virulent African swine fever virus (ASFV) isolate (Malawi LIL20/1) identified an open reading frame of 1191 amino acid residues encoding a protein of 134.9 kDa. This gene mapped to the SalI i and j restriction endonuclease fragments of the ASFV genome. The predicted polypeptide was found to share 21.1% identity over a 1077 amino acid region with the human type II DNA topoisomerase. The sequence is compared to other type II DNA topoisomerases and the possible roles in ASFV replication are discussed.Entities:
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Year: 1992 PMID: 1335084 DOI: 10.1016/0022-2836(92)90887-p
Source DB: PubMed Journal: J Mol Biol ISSN: 0022-2836 Impact factor: 5.469