Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Corticotropin-releasing factor-induced immunosuppression in human and invertebrate immunocytes.

Literature DB >> 1334807

Corticotropin-releasing factor-induced immunosuppression in human and invertebrate immunocytes.

E M Smith¹, T K Hughes, P Cadet, G B Stefano.

Abstract

1. Corticotropin-releasing factor (CRF) appears to be a potentially important signal molecule in both vertebrate and invertebrate neuroimmune and autoimmunoregulatory processes. It appears to mimic the effects of alpha-melanocyte stimulating hormone (MSH) but has a longer duration of action. 2. alpha-Helical CRF, a specific inhibitor of CRF, antagonizes CRF-induced cellular immunosuppression but is ineffective in altering MSH-induced immunosuppression. 3. Both human and Mytilus immunocytes appear to have specific CRF receptors. 4. In another experiment, both CRF and MSH antagonize tumor necrosis factor stimulation of immunocytes. Again, alpha-helical CRF antagonizes only CRF activity, further suggesting the presence of a separate CRF receptor on these cells.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1992 PMID： 1334807 DOI： 10.1007/bf00711548

Source DB: PubMed Journal: Cell Mol Neurobiol ISSN： 0272-4340 Impact factor: 5.046

16 in total

1. A neuroimmunoregulatory-like mechanism responding to stress in the marine bivalve Mytilus edulis.

Authors: G B Stefano; P Cadet; A Dokun; B Scharrer
Journal: Brain Behav Immun Date: 1990-12 Impact factor: 7.217

2. Localization, colocalization, and plasticity of corticotropin-releasing factor immunoreactivity in rat brain.

Authors: P E Sawchenko; L W Swanson
Journal: Fed Proc Date: 1985-01

3. Release of corticotropin-releasing factor from rat brain regions in vitro.

Authors: M A Smith; G Bissette; T A Slotkin; D L Knight; C B Nemeroff
Journal: Endocrinology Date: 1986-05 Impact factor: 4.736

Review 4. Nucleus locus ceruleus: new evidence of anatomical and physiological specificity.

Authors: S L Foote; F E Bloom; G Aston-Jones
Journal: Physiol Rev Date: 1983-07 Impact factor: 37.312

5. Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus.

Authors: R J Valentino; S L Foote; G Aston-Jones
Journal: Brain Res Date: 1983-07-04 Impact factor: 3.252

6. Corticotropin releasing factor (CRF): immunoreactive neurones and fibers in rat hypothalamus.

Authors: F E Bloom; E L Battenberg; J Rivier; W Vale
Journal: Regul Pept Date: 1982-06

7. Downregulation of enkephalin-mediated inflammatory responses by CD10/neutral endopeptidase 24.11.

Authors: M A Shipp; G B Stefano; L D'Adamio; S N Switzer; F D Howard; J Sinisterra; B Scharrer; E L Reinherz
Journal: Nature Date: 1990-09-27 Impact factor: 49.962

8. Stimulatory effects of opioid neuropeptides on locomotory activity and conformational changes in invertebrate and human immunocytes: evidence for a subtype of delta receptor.

Authors: G B Stefano; P Cadet; B Scharrer
Journal: Proc Natl Acad Sci U S A Date: 1989-08 Impact factor: 11.205

9. Beta-endorphin and met-enkephalin stimulate human peripheral blood mononuclear cell chemotaxis.

Authors: D E van Epps; L Saland
Journal: J Immunol Date: 1984-06 Impact factor: 5.422

10. Immunosuppression in the definitive and intermediate hosts of the human parasite Schistosoma mansoni by release of immunoactive neuropeptides.

Authors: O Duvaux-Miret; G B Stefano; E M Smith; C Dissous; A Capron
Journal: Proc Natl Acad Sci U S A Date: 1992-01-15 Impact factor: 11.205

5 in total

Corticotropin-releasing factor-induced immunosuppression in human and invertebrate immunocytes.

1. A neuroimmunoregulatory-like mechanism responding to stress in the marine bivalve Mytilus edulis.

2. Localization, colocalization, and plasticity of corticotropin-releasing factor immunoreactivity in rat brain.

3. Release of corticotropin-releasing factor from rat brain regions in vitro.

Review 4. Nucleus locus ceruleus: new evidence of anatomical and physiological specificity.

5. Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus.

6. Corticotropin releasing factor (CRF): immunoreactive neurones and fibers in rat hypothalamus.

7. Downregulation of enkephalin-mediated inflammatory responses by CD10/neutral endopeptidase 24.11.

8. Stimulatory effects of opioid neuropeptides on locomotory activity and conformational changes in invertebrate and human immunocytes: evidence for a subtype of delta receptor.

9. Beta-endorphin and met-enkephalin stimulate human peripheral blood mononuclear cell chemotaxis.

10. Immunosuppression in the definitive and intermediate hosts of the human parasite Schistosoma mansoni by release of immunoactive neuropeptides.

1. Corticotropin Releasing Factor (CRF) activation of NF-kappaB-directed transcription in leukocytes.

Review 2. Invertebrate and vertebrate neuroimmune and autoimmunoregulatory commonalties involving opioid peptides.

3. Neuropeptides as signal molecules in common with leukocytes and the hypothalamic-pituitary-adrenal axis.

4. Evidence for the production and action of interleukin-10 in pituitary cells.

5. Opioid peptides and opiate alkaloids in immunoregulatory processes.