Literature DB >> 13242740

Effect of ethionine-induced pancreatic damage on iron absorption.

T D KINNEY, N KAUFMAN, J KLAVINS.   

Abstract

Groups of rats were fed a diet of the purified type which was supplemented by dl-ethionine to produce pancreatic damage. It was shown that animals with pancreatic damage absorbed more iron from the gastrointestinal tract than control animals without pancreatic damage. When iron was added to the diet the animals with pancreatic damage absorbed even greater quantities of iron. These findings in rats were corroborated by similar findings in mice.

Entities:  

Keywords:  ETHIONINE/injurious effects; IRON/metabolism; PANCREAS/physiology

Mesh:

Substances:

Year:  1955        PMID: 13242740      PMCID: PMC2136497          DOI: 10.1084/jem.102.2.151

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  10 in total

1.  Effects of DL-ethionine on the pancreas and other organs.

Authors:  M ALVIZOURI; S WARREN
Journal:  AMA Arch Pathol       Date:  1954-02

2.  Cellular changes accompanying the degenerative and regenerative phase of ethionine-induced pancreatic damage in the rat.

Authors:  M WACHSTEIN; E MEISEL
Journal:  Lab Invest       Date:  1953 Jul-Aug       Impact factor: 5.662

3.  Nephrotoxic action of dl-ethionine.

Authors:  M WACHSTEIN; E MEISEL
Journal:  Proc Soc Exp Biol Med       Date:  1951-08

4.  Hepatic fibrosis produced by chronic ethionine feeding.

Authors:  D KOCH WESER; H POPPER
Journal:  Proc Soc Exp Biol Med       Date:  1952-01

5.  Selective pancreatic acinar destruction by diethionine.

Authors:  R C GOLDBERG; I L CHAIKOFF
Journal:  AMA Arch Pathol       Date:  1951-09

6.  Hemochromatosis; an investigation of twenty-three cases with special reference to nutrition, to iron metabolism, and to studies of hepatic and pancreatic function.

Authors:  T L ALTHAUSEN; R K DOIG; S WEIDEN; R MOTTERAM; C N TURNER; A MOORE
Journal:  Trans Assoc Am Physicians       Date:  1950

7.  Destruction of pancreatic acinar tissue by DL-ethionine.

Authors:  R C GOLDBERG; I L CHAIKOFF; A H DODGE
Journal:  Proc Soc Exp Biol Med       Date:  1950-08

8.  RADIOACTIVE IRON AND ITS EXCRETION IN URINE, BILE, AND FECES.

Authors:  P F Hahn; W F Bale; R A Hettig; M D Kamen; G H Whipple
Journal:  J Exp Med       Date:  1939-10-31       Impact factor: 14.307

9.  The influence of diet on iron absorption; the pathology of iron excess.

Authors:  T D KINNEY; D M HEGSTED; C A FINCH
Journal:  J Exp Med       Date:  1949-08-01       Impact factor: 14.307

10.  The influence of diet on iron absorption; the interrelation of iron and phosphorus.

Authors:  D M HEGSTED; C A FINCH; T D KINNEY
Journal:  J Exp Med       Date:  1949-08-01       Impact factor: 14.307

  10 in total
  18 in total

Review 1.  Iron nutrition.

Authors:  J D Cook; C A Finch
Journal:  West J Med       Date:  1975-06

2.  EFFECT OF ALCOHOL ON IRON ABSORPTION.

Authors:  R W CHARLTON; P JACOBS; H SEFTEL; T H BOTHWELL
Journal:  Br Med J       Date:  1964-12-05

3.  CURRENT CONCEPTS OF IRON METABOLISM-II.

Authors:  A R COX; W A DODDS; W G TRAPP
Journal:  Can Med Assoc J       Date:  1963-12-07       Impact factor: 8.262

4.  ABSORPTION OF IRON IN CIRRHOSIS OF LIVER.

Authors:  S T CALLENDER; J S MALPAS
Journal:  Br Med J       Date:  1963-12-14

5.  SEQUENCE OF DEPOSITION AND LOSS OF STAINABLE IRON IN THE LIVER DURING ETHIONINE ADMINISTRATION.

Authors:  N KAUFMAN; J V KLAVINS; T D KINNEY
Journal:  Am J Pathol       Date:  1964-12       Impact factor: 4.307

6.  ALCOHOLISM AND IRON METABOLISM.

Authors:  C R PENGELLY
Journal:  Br Med J       Date:  1965-05-22

7.  CHANGES IN AFFINITY OF LIVER FOR IRON AND LOSS OF LIVER IRON DURING PROLONGED ETHIONINE ADMINISTRATION.

Authors:  J V KLAVINS; T KINNEY; N KAUFMAN
Journal:  Am J Pathol       Date:  1965-06       Impact factor: 4.307

8.  Iron overloading and hepatic vulnerability.

Authors:  L GOLBERG; J P SMITH
Journal:  Am J Pathol       Date:  1960-02       Impact factor: 4.307

9.  The influence of dietary protein on iron absorption.

Authors:  J V KLAVINS; T D KINNEY; N KAUFMAN
Journal:  Br J Exp Pathol       Date:  1962-04

10.  The intestine in iron metabolism; its role in normal and abnormal states.

Authors:  T H BOTHWELL; C A FINCH
Journal:  Am J Dig Dis       Date:  1957-04
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