| Literature DB >> 1324125 |
T Murayama1, F Jisaki, M Ayata, D Sakamuro, T Hironaka, K Hirai, N Tsuchiya, K Ito, T Furukawa.
Abstract
Synovial fluid from 20 patients with rheumatoid arthritis was analyzed to detect human cytomegalovirus (CMV) genomic material using polymerase chain reaction. Of 20 samples tested, 9 were positive for CMV by either ethidium bromide staining or Southern blotting. In contrast, CMV was detected in only 2 of 18 control patients with osteoarthritis. These results suggest an etiologic relationship between CMV and rheumatoid arthritis.Entities:
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Year: 1992 PMID: 1324125
Source DB: PubMed Journal: Clin Exp Rheumatol ISSN: 0392-856X Impact factor: 4.473