Literature DB >> 1318948

Cell growth effects of Epstein-Barr virus leader protein.

G J Allan1, G J Inman, B D Parker, D T Rowe, P J Farrell.   

Abstract

B lymphoblastoid cell lines immortalized with P3HR1/633 Epstein-Barr virus (EBV), which has a deletion in the EBV nuclear antigen leader protein (EBNA-LP) gene, were transfected with a vector expressing wild-type EBNA-LP. The EBNA-LP transfectants grew out faster under G418 selection than control cells but expression of EBNA-LP made no significant difference to growth rate or saturation density of the resulting established cell lines. When the cells expressing EBNA-LP were allowed to grow to saturation and then diluted in fresh medium they underwent DNA synthesis more rapidly than control cultures.

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Year:  1992        PMID： 1318948     DOI： 10.1099/0022-1317-73-6-1547

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  20 in total

1.  Conserved region CR2 of Epstein-Barr virus nuclear antigen leader protein is a multifunctional domain that mediates self-association as well as nuclear localization and nuclear matrix association.

Authors:  Michiko Tanaka; Akihiko Yokoyama; Mie Igarashi; Go Matsuda; Kentaro Kato; Mikiko Kanamori; Kanji Hirai; Yasushi Kawaguchi; Yuji Yamanashi
Journal:  J Virol       Date:  2002-02       Impact factor: 5.103

2.  Interaction of Epstein-Barr virus nuclear antigen leader protein (EBNA-LP) with HS1-associated protein X-1: implication of cytoplasmic function of EBNA-LP.

Authors:  Y Kawaguchi; K Nakajima; M Igarashi; T Morita; M Tanaka; M Suzuki; A Yokoyama; G Matsuda; K Kato; M Kanamori; K Hirai
Journal:  J Virol       Date:  2000-11       Impact factor: 5.103

Review 3.  The expression and function of Epstein-Barr virus encoded latent genes.

Authors:  L S Young; C W Dawson; A G Eliopoulos
Journal:  Mol Pathol       Date:  2000-10

4.  The Epstein-Barr virus EBNA-LP protein preferentially coactivates EBNA2-mediated stimulation of latent membrane proteins expressed from the viral divergent promoter.

Authors:  Rongsheng Peng; Stephanie C Moses; Jie Tan; Elisabeth Kremmer; Paul D Ling
Journal:  J Virol       Date:  2005-04       Impact factor: 5.103

5.  Multiple functions within the Epstein-Barr virus EBNA-3A protein.

Authors:  I Cludts; P J Farrell
Journal:  J Virol       Date:  1998-03       Impact factor: 5.103

6.  Mediation of Epstein-Barr virus EBNA-LP transcriptional coactivation by Sp100.

Authors:  Paul D Ling; Rong Sheng Peng; Ayako Nakajima; Jiang H Yu; Jie Tan; Stephanie M Moses; Wei-Hong Yang; Bo Zhao; Elliott Kieff; Kenneth D Bloch; Donald B Bloch
Journal:  EMBO J       Date:  2005-09-22       Impact factor: 11.598

7.  Cell cycle stage-specific phosphorylation of the Epstein-Barr virus immortalization protein EBNA-LP.

Authors:  M K Kitay; D T Rowe
Journal:  J Virol       Date:  1996-11       Impact factor: 5.103

Review 8.  The small RNAs of Epstein-Barr virus.

Authors:  M J Clemens
Journal:  Mol Biol Rep       Date:  1993-02       Impact factor: 2.316

9.  Comparative analysis of the regulation of the interferon-inducible protein kinase PKR by Epstein-Barr virus RNAs EBER-1 and EBER-2 and adenovirus VAI RNA.

Authors:  T V Sharp; M Schwemmle; I Jeffrey; K Laing; H Mellor; C G Proud; K Hilse; M J Clemens
Journal:  Nucleic Acids Res       Date:  1993-09-25       Impact factor: 16.971

Review 10.  Epstein-Barr virus: more than 50 years old and still providing surprises.

Authors:  Lawrence S Young; Lee Fah Yap; Paul G Murray
Journal:  Nat Rev Cancer       Date:  2016-09-30       Impact factor: 60.716
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