Literature DB >> 1316311

Topoisomerase-targeting antitumor drugs: mechanisms of cytotoxicity and resistance.

L F Liu, P D'Arpa.   

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Year:  1992        PMID: 1316311

Source DB:  PubMed          Journal:  Important Adv Oncol        ISSN: 0883-5896


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  12 in total

1.  The geometry of DNA supercoils modulates topoisomerase-mediated DNA cleavage and enzyme response to anticancer drugs.

Authors:  A Kathleen McClendon; Neil Osheroff
Journal:  Biochemistry       Date:  2006-03-07       Impact factor: 3.162

2.  Determining success rates of the current pharmacokinetically guided dosing approach of topotecan in pediatric oncology patients.

Authors:  Anna Birg Mitchell; Aksana Vasilyeva; Amar Gajjar; Victor M Santana; Clinton F Stewart
Journal:  Pediatr Blood Cancer       Date:  2018-12-11       Impact factor: 3.167

3.  SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage.

Authors:  Y Mao; M Sun; S D Desai; L F Liu
Journal:  Proc Natl Acad Sci U S A       Date:  2000-04-11       Impact factor: 11.205

4.  Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition.

Authors:  Komaraiah Palle; Cyrus Vaziri
Journal:  Cell Cycle       Date:  2011-05-15       Impact factor: 4.534

5.  Human topoisomerase I mediates illegitimate recombination leading to DNA insertion into the ribosomal DNA locus in Saccharomyces cerevisiae.

Authors:  J Zhu; R H Schiestl
Journal:  Mol Genet Genomics       Date:  2004-03-06       Impact factor: 3.291

Review 6.  Topoisomerase II in multiple drug resistance.

Authors:  G A Hofmann; M R Mattern
Journal:  Cytotechnology       Date:  1993       Impact factor: 2.058

Review 7.  DNA topoisomerase II, genotoxicity, and cancer.

Authors:  A Kathleen McClendon; Neil Osheroff
Journal:  Mutat Res       Date:  2007-07-03       Impact factor: 2.433

8.  Mechanism of Action of Mycobacterium tuberculosis Gyrase Inhibitors: A Novel Class of Gyrase Poisons.

Authors:  Elizabeth G Gibson; Tim R Blower; Monica Cacho; Ben Bax; James M Berger; Neil Osheroff
Journal:  ACS Infect Dis       Date:  2018-05-17       Impact factor: 5.084

Review 9.  Topoisomerase I inhibitors: the relevance of prolonged exposure for present clinical development.

Authors:  C J Gerrits; M J de Jonge; J H Schellens; G Stoter; J Verweij
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

10.  Importance of the fourth alpha-helix within the CAP homology domain of type II topoisomerase for DNA cleavage site recognition and quinolone action.

Authors:  Dirk Strumberg; John L Nitiss; Jiaowang Dong; Jerrylaine Walker; Marc C Nicklaus; Kurt W Kohn; Jonathan G Heddle; Anthony Maxwell; Siegfried Seeber; Yves Pommier
Journal:  Antimicrob Agents Chemother       Date:  2002-09       Impact factor: 5.191

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