| Literature DB >> 1315297 |
C J Miller1, N J Alexander, A Gettie, A G Hendrickx, P A Marx.
Abstract
The ability of two nonoxynol-9 spermicide preparations to prevent the genital transmission of SIV in rhesus macaques was compared. Administration of one mL of contraceptive foam before the intravaginal inoculation of cell-free SIV prevented the genital transmission of SIV to three of six animals, and using one mL of contraceptive gel prevented the genital transmission of SIV to two of six animals. Thus, both contraceptive foams and gels containing nonoxynol-9 provided protection against the genital transmission of SIV.Entities:
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Year: 1992 PMID： 1315297
Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329