Literature DB >> 1314926

[Comparison of DNA analysis with histomorphologic parameters in stomach cancer].

T Böttger1, H Gabbert, M Stöckle, S Wellek, H Menke, H C Jauckus, A Grenz, A Heintz, T Junginger.   

Abstract

After curative resection of stomach carcinomas (adenocarcinomas: n = 58, signet ring cell carcinomas: n = 24, undifferentiated carcinomas: n = 21) the DNA content of the tumor cells was compared with the histomorphological parameters. There was a correlation between the DNA content and the histomorphological parameters. The DNA analysis had no additionally prognostic influence. In the multivariate regression analysis the prognosis depended on lymph node status (p = 0.0009), pT-stage (p = 0.02), tumor localization (p = 0.03) and the histological type (p = 0.05). The prognosis was independent of the DNA content. Furthermore, neither did the degree of differentiation, the operative procedure, the safety distance, the size of the tumor, the sex nor the age of the patient have any influence on the prognosis.

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Year:  1992        PMID: 1314926     DOI: 10.1007/bf00186141

Source DB:  PubMed          Journal:  Langenbecks Arch Chir        ISSN: 0023-8236


  21 in total

1.  Flow cytometric analysis in colorectal carcinoma: prognostic significance of cellular DNA content.

Authors:  A Schillaci; D D Tirindelli; M Ferri; L Teodori; F Mauro; V Nicolanti; S Stipa
Journal:  Int J Colorectal Dis       Date:  1990-12       Impact factor: 2.571

2.  [Image analytic DNA cytometry--a possibility for assessment of prognosis after resection of ductal pancreatic cancers?].

Authors:  T Böttger; S Störkel; M Stöckle; B Gerber; T Junginger
Journal:  Chirurg       Date:  1991-10       Impact factor: 0.955

3.  Intratumoral regional differences in DNA ploidy of gastrointestinal carcinomas.

Authors:  K Sasaki; T Hashimoto; K Kawachino; M Takahashi
Journal:  Cancer       Date:  1988-12-15       Impact factor: 6.860

4.  Cell proliferation and differentiation in intramucosal and advanced signet ring cell carcinomas of the human stomach.

Authors:  H Sugihara; T Hattori; M Fukuda; S Fujita
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1987

5.  DNA image cytometry. A prognostic tool in squamous cell carcinoma of the esophagus?

Authors:  T Böttger; S Störkel; M Stöckle; W Wahl; M Jugenheimer; O Effenberger-Kim; T Vinh; T Junginger
Journal:  Cancer       Date:  1991-05-01       Impact factor: 6.860

6.  Regional ploidy variations in signet ring cell carcinomas of the stomach.

Authors:  H Sugihara; T Hattori; S Fujita; K Hirose; M Fukuda
Journal:  Cancer       Date:  1990-01-01       Impact factor: 6.860

7.  Heterogeneity of DNA ploidy in patients with undifferentiated carcinomas of the stomach.

Authors:  M Haraguchi; T Okamura; D Korenaga; S Tsujitani; P Marin; K Sugimachi
Journal:  Cancer       Date:  1987-03-01       Impact factor: 6.860

8.  DNA flow cytometry of histological material from human gastric cancer.

Authors:  J C Macartney; R S Camplejohn; G Powell
Journal:  J Pathol       Date:  1986-04       Impact factor: 7.996

9.  DNA distribution patterns in early gastric carcinomas. A Feulgen cytometric study of gastric brush smears.

Authors:  B Czerniak; F Herz; L G Koss
Journal:  Cancer       Date:  1987-01-01       Impact factor: 6.860

10.  DNA ploidy is closely linked to tumor invasion, lymph node metastasis, and prognosis in clinical gastric cancer.

Authors:  D Korenaga; T Okamura; A Saito; H Baba; K Sugimachi
Journal:  Cancer       Date:  1988-07-15       Impact factor: 6.860

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