Literature DB >> 1312021

A new cyclopyrophosphate as a bacterial antistressor?

D Ostrovsky1, I Shipanova, L Sibeldina, A Shashkov, E Kharatian, I Malyarova, G Tantsyrev.   

Abstract

In a number of bacteria an unusual glycosyl pyrophosphate (31P NMR signal chemical shift at about -15 ppm) was detected when the cells were subjected to oxidative stress. This substance from Brevibacterium ammoniagenes has now been identified as 2-methyl-butan-1,2,3,4,-tetraol-2,4-cyclopyrophosphate, which is accumulated in the cell under certain conditions in concentrations of of about 50 mM. It is now suggested that this compound is the long sought after bacterial antistressor.

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Year:  1992        PMID: 1312021     DOI: 10.1016/0014-5793(92)80045-i

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  6 in total

1.  Structure determination of a novel cyclic phosphocompound isolated from Desulfovibrio desulfuricans.

Authors:  D L Turner; H Santos; P Fareleira; I Pacheco; J LeGall; A V Xavier
Journal:  Biochem J       Date:  1992-07-15       Impact factor: 3.857

2.  Bacterial oxidative-stress substance is 2-C-methyl-D-erythritol 2,4-cyclopyrophosphate.

Authors:  D Ostrovsky; A Shashkov; A Sviridov
Journal:  Biochem J       Date:  1993-11-01       Impact factor: 3.857

3.  Methylerythritol cyclodiphosphate (MEcPP) in deoxyxylulose phosphate pathway: synthesis from an epoxide and mechanisms.

Authors:  Youli Xiao; Rodney L Nyland; Caren L Freel Meyers; Pinghua Liu
Journal:  Chem Commun (Camb)       Date:  2010-09-01       Impact factor: 6.222

4.  New compatible solutes related to Di-myo-inositol-phosphate in members of the order Thermotogales.

Authors:  L O Martins; L S Carreto; M S Da Costa; H Santos
Journal:  J Bacteriol       Date:  1996-10       Impact factor: 3.490

5.  2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activity.

Authors:  J Kipchirchir Bitok; Caren Freel Meyers
Journal:  ACS Chem Biol       Date:  2012-08-06       Impact factor: 5.100

6.  Functional analysis of the final steps of the 1-deoxy-D-xylulose 5-phosphate (DXP) pathway to isoprenoids in plants using virus-induced gene silencing.

Authors:  Jonathan E Page; Gerd Hause; Maja Raschke; Wenyun Gao; Jürgen Schmidt; Meinhart H Zenk; Toni M Kutchan
Journal:  Plant Physiol       Date:  2004-04-02       Impact factor: 8.340

  6 in total

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