Literature DB >> 1306049

Assessment of specimen fixation in a surgical pathology service.

R D Start1, S S Cross, J H Smith.   

Abstract

The quality of specimen fixation was examined within a routine diagnostic histopathology service. For each specimen the adequacy of fixation was assessed and the transit time between operating theatre and the laboratory was measured. Preliminary fixation was found to be inadequate in 25% of specimens and some form of manipulation to assist fixation was required in 36% of specimens. The mean transit time was 22 (SD 10.7) hours. Specimen fixation and transport are additional factors to consider in quality assurance of histopathology.

Mesh:

Year:  1992        PMID: 1306049      PMCID: PMC495239          DOI: 10.1136/jcp.45.6.546

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  6 in total

1.  Specimen transport audit.

Authors:  P Garner; R G Masterton
Journal:  J Clin Pathol       Date:  1990-09       Impact factor: 3.411

2.  Audit of turn-around times in a microbiology laboratory.

Authors:  S Rogers; M J Bywater; D S Reeves
Journal:  J Clin Pathol       Date:  1991-03       Impact factor: 3.411

3.  Does delay in fixation affect the number of mitotic figures in processed tissue?

Authors:  S S Cross; R D Start; J H Smith
Journal:  J Clin Pathol       Date:  1990-07       Impact factor: 3.411

4.  The effects of progressive formaldehyde fixation on the preservation of tissue antigens.

Authors:  A S Leong; P N Gilham
Journal:  Pathology       Date:  1989-10       Impact factor: 5.306

5.  Is the grading of breast carcinomas affected by a delay in fixation?

Authors:  R D Start; M S Flynn; S S Cross; K Rogers; J H Smith
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1991

6.  Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms.

Authors:  P A Hall; D A Levison; A L Woods; C C Yu; D B Kellock; J A Watkins; D M Barnes; C E Gillett; R Camplejohn; R Dover
Journal:  J Pathol       Date:  1990-12       Impact factor: 7.996

  6 in total
  8 in total

Review 1.  Effect of fixatives and tissue processing on the content and integrity of nucleic acids.

Authors:  Mythily Srinivasan; Daniel Sedmak; Scott Jewell
Journal:  Am J Pathol       Date:  2002-12       Impact factor: 4.307

2.  The feasibility of computer-aided monitoring of the workflow in surgical pathology: a five-year experience.

Authors:  Chih-En Tseng; Hsiu-Huei Chiang; Liang-Yu Shih; Kai-Sheng Liao
Journal:  J Med Syst       Date:  2014-02-04       Impact factor: 4.460

3.  Value of adequate fixation for accurate histological interpretation.

Authors:  M Kudo
Journal:  J Clin Pathol       Date:  1993-02       Impact factor: 3.411

4.  Evaluating the Feasibility of DNA Methylation Analyses Using Long-Term Archived Brain Formalin-Fixed Paraffin-Embedded Samples.

Authors:  Stine T Bak; Nicklas H Staunstrup; Anna Starnawska; Tina F Daugaard; Jens R Nyengaard; Mette Nyegaard; Anders Børglum; Ole Mors; Karl-Anton Dorph-Petersen; Anders L Nielsen
Journal:  Mol Neurobiol       Date:  2016-12-19       Impact factor: 5.590

Review 5.  RNA expression analysis from formalin fixed paraffin embedded tissues.

Authors:  Susan M Farragher; Austin Tanney; Richard D Kennedy; D Paul Harkin
Journal:  Histochem Cell Biol       Date:  2008-08-05       Impact factor: 4.304

6.  Prognostic value of proliferation assay in the luminal, HER2-positive, and triple-negative biologic classes of breast cancer.

Authors:  Mohammed A Aleskandarany; Andrew R Green; Ahmed A Benhasouna; Fabricio F Barros; Keith Neal; Jorge S Reis-Filho; Ian O Ellis; Emad A Rakha
Journal:  Breast Cancer Res       Date:  2012-01-06       Impact factor: 6.466

7.  Quantitative assessment shows loss of antigenic epitopes as a function of pre-analytic variables.

Authors:  Yalai Bai; Juliana Tolles; Huan Cheng; Summar Siddiqui; Arun Gopinath; Eirini Pectasides; Robert L Camp; David L Rimm; Annette M Molinaro
Journal:  Lab Invest       Date:  2011-04-25       Impact factor: 5.662

8.  Practical Guidelines for Collection, Manipulation and Inactivation of SARS-CoV-2 and COVID-19 Clinical Specimens.

Authors:  William Bain; Janet S Lee; Alan M Watson; Molly S Stitt-Fischer
Journal:  Curr Protoc Cytom       Date:  2020-06
  8 in total

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