Literature DB >> 1301997

Automated DNA sequencing and analysis of 106 kilobases from human chromosome 19q13.3.

A Martin-Gallardo1, W R McCombie, J D Gocayne, M G FitzGerald, S Wallace, B M Lee, J Lamerdin, S Trapp, J M Kelley, L I Liu.   

Abstract

A total of 116,118 basepairs (bp) derived from three cosmids spanning the ERCC1 locus of human chromosome 19q13.3 have been sequenced with automated fluorescence-based sequencers and analysed by polymerase chain reaction amplification and computer methods. The assembled sequence forms two contigs totalling 105,831 bp, which contain a human fosB proto-oncogene, a gene encoding a protein phosphatase, two genes of unknown function and the previously-characterized ERCC1 DNA repair gene. This light band region has a high average density of 1.4 Alu repeats per kilobase. Human chromosome light bands could therefore contain up to 75,000 genes and 1.5 million Alu repeats.

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Year:  1992        PMID： 1301997     DOI： 10.1038/ng0492-34

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  13 in total

1.  Nspl1, a new Z-band-associated protein.

Authors:  J G Geisler; R J Palmer; L J Stubbs; M L Mucenski
Journal:  J Muscle Res Cell Motil       Date:  1999-10       Impact factor: 2.698

2.  The prediction of exons through an analysis of spliceable open reading frames.

Authors:  G B Hutchinson; M R Hayden
Journal:  Nucleic Acids Res       Date:  1992-07-11       Impact factor: 16.971

3.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1992-07-25       Impact factor: 16.971

4.  Binding sites for adeno-associated virus Rep proteins within the human genome.

Authors:  R S Wonderling; R A Owens
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

5.  Statistical analysis of vertebrate sequences reveals that long genes are scarce in GC-rich isochores.

Authors:  L Duret; D Mouchiroud; C Gautier
Journal:  J Mol Evol       Date:  1995-03       Impact factor: 2.395

6.  Synthesis and polymerase incorporation of 5'-amino-2',5'-dideoxy-5'-N-triphosphate nucleotides.

Authors:  Jia Liu Wolfe; Tomohiko Kawate; Alexei Belenky; Vincent Stanton
Journal:  Nucleic Acids Res       Date:  2002-09-01       Impact factor: 16.971

7.  Partial sequence analysis of 130 randomly selected maize cDNA clones.

Authors:  C S Keith; D O Hoang; B M Barrett; B Feigelman; M C Nelson; H Thai; C Baysdorfer
Journal:  Plant Physiol       Date:  1993-01       Impact factor: 8.340

8.  Number of CpG islands and genes in human and mouse.

Authors:  F Antequera; A Bird
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-15       Impact factor: 11.205

9.  Structure of the human DNA ligase I gene.

Authors:  P Noguiez; D E Barnes; H W Mohrenweiser; T Lindahl
Journal:  Nucleic Acids Res       Date:  1992-08-11       Impact factor: 16.971

10.  Lamprey lymphocyte-like cells express homologs of genes involved in immunologically relevant activities of mammalian lymphocytes.

Authors:  Tatiana Uinuk-Ool; Werner E Mayer; Akie Sato; Roman Dongak; Max D Cooper; Jan Klein
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-21       Impact factor: 11.205
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