Literature DB >> 1296924

Protective efficacy of different cell-wall fractions of Mycobacterium tuberculosis.

I B Chugh1, R Kansal, V K Vinayak, G K Khuller.   

Abstract

Immunization with various cell-wall fractions of M. tuberculosis H37Ra, progressively depleted of lipids (cell-wall-insoluble fraction; CWIF), soluble proteins (cell-wall core; CWC), mycolic acids and arabinogalactans (cell-wall-protein-peptidoglycan complex; CW-PPC) elicited significant levels of both humoral and cell-mediated immune response. Mice immunized with these fractions, when challenged with an LD50 dose of M. tuberculosis H37Rv, exhibited significant protection as revealed by high survival rates and decreased bacterial load in lungs, liver and spleen, as compared to nonimmunized animals.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1296924     DOI： 10.1007/bf02899898

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  17 in total

1.  Suppression of antigen and mitogen induced human T lymphocyte DNA synthesis by bacterial lipopolysaccharide: mediation by monocyte activation and production of prostaglandins.

Authors:  J J Ellner; P J Spagnuolo
Journal:  J Immunol       Date:  1979-12       Impact factor: 5.422

2.  The stereoisomers of alpha epsilon-diaminopimelic acid. II. Their distribution in the bacterial order Actinomycetales and in certain Eubacteriales.

Authors:  D S HOARE; E WORK
Journal:  Biochem J       Date:  1957-03       Impact factor: 3.857

3.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

4.  Effective vaccination of mice against leprosy bacilli with subunits of Mycobacterium leprae.

Authors:  R H Gelber; P J Brennan; S W Hunter; M W Munn; J M Monson; L P Murray; P Siu; M Tsang; E G Engleman; N Mohagheghpour
Journal:  Infect Immun       Date:  1990-03       Impact factor: 3.441

Review 5.  Mycobacterial antigens: a review of their isolation, chemistry, and immunological properties.

Authors:  T M Daniel; B W Janicki
Journal:  Microbiol Rev       Date:  1978-03

6.  Macromolecular biosynthesis in Mycobacterium smegmatis ATCC 607 in the presence of antibodies to mannophosphoinositides.

Authors:  G K Khuller; A Dogra; U Malik; S Asotra
Journal:  J Gen Microbiol       Date:  1984-07

7.  Duration of immunity to tuberculosis in mice vaccinated intravenously with oil-treated cell walls of Mycobacterium bovis strain BCG.

Authors:  R L Anacker; W R Barclay; W Brehmer; C L Larson; E Ribi
Journal:  J Immunol       Date:  1967-06       Impact factor: 5.422

8.  Immunogenicity of ribonucleic acid-protein fraction of Mycobacterium tuberculosis encapsulated in liposomes.

Authors:  P Pancholi; V K Vinayak; G K Khuller
Journal:  J Med Microbiol       Date:  1989-06       Impact factor: 2.472

9.  Isolation and characterization of the highly immunogenic cell wall-associated protein of Mycobacterium leprae.

Authors:  S W Hunter; M McNeil; R L Modlin; V Mehra; B R Bloom; P J Brennan
Journal:  J Immunol       Date:  1989-04-15       Impact factor: 5.422

10.  Factors influencing protection against experimental tuberculosis in mice by heat-stable cell wall vaccines.

Authors:  E Ribi; R L Anacker; W Brehmer; G Goode; C L Larson; R H List; K C Milner; W C Wicht
Journal:  J Bacteriol       Date:  1966-10       Impact factor: 3.490
View more
  1 in total

1.  Host response to Mycobacterial cell wall subunit during experimental tuberculosis in mice.

Authors:  I B Chugh; V K Vinayak; G K Khuller
Journal:  Folia Microbiol (Praha)       Date:  1993       Impact factor: 2.099
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.