| Literature DB >> 12967035 |
M R K Sartori1, J B Pretto, A B Cruz, L F V Bresciani, R A Yunes, M Sortino, S A Zacchino, V Filho Cechinel.
Abstract
Wedelia paludosa (Acmela brasiliensis) (Asteraceae), a traditionally used native Brazilian medicinal plant, showed antifungal activity against dermatophytes in dilution tests. The hexane, dichloromethane and butanol fractions displayed activity against Epidermophyton floccosum, Trichophyton rubrum and Trichophyton mentagrophytes, with minimal inhibitory concentrations between 250 and 1000 microg/mL. Two pure compounds, identified as kaurenoic acid (1) and luteolin (2), also showed activity against these dermatophytes.Entities:
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Year: 2003 PMID： 12967035
Source DB: PubMed Journal: Pharmazie ISSN： 0031-7144 Impact factor: 1.267