Literature DB >> 12964834

Natural products--a simple model to explain chemical diversity.

Richard D Firn1, Clive G Jones.   

Abstract

A simple evolutionary model is presented which explains why organisms produce so many natural products, why so many have low biological activity, why enzymes involved in natural product synthesis have the properties they do and why natural product metabolism is shaped as it is.

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Year:  2003        PMID： 12964834     DOI： 10.1039/b208815k

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  82 in total

1.  Phytochemical diversity drives plant-insect community diversity.

Authors:  Lora A Richards; Lee A Dyer; Matthew L Forister; Angela M Smilanich; Craig D Dodson; Michael D Leonard; Christopher S Jeffrey
Journal:  Proc Natl Acad Sci U S A       Date:  2015-08-17       Impact factor: 11.205

2.  Hill coefficients of dietary polyphenolic enzyme inhibitiors: can beneficial health effects of dietary polyphenols be explained by allosteric enzyme denaturing?

Authors:  Nikolai Kuhnert; Farnoosh Dairpoosh; Rakesh Jaiswal; Marius Matei; Sagar Deshpande; Agnieszka Golon; Hany Nour; Hande Karaköse; Nadim Hourani
Journal:  J Chem Biol       Date:  2011-01-29

3.  Evolutionary radiation of lanthipeptides in marine cyanobacteria.

Authors:  Andres Cubillos-Ruiz; Jessie W Berta-Thompson; Jamie W Becker; Wilfred A van der Donk; Sallie W Chisholm
Journal:  Proc Natl Acad Sci U S A       Date:  2017-06-19       Impact factor: 11.205

4.  Synthesis of a 10,000-membered library of molecules resembling carpanone and discovery of vesicular traffic inhibitors.

Authors:  Brian C Goess; Rami N Hannoush; Lawrence K Chan; Tomas Kirchhausen; Matthew D Shair
Journal:  J Am Chem Soc       Date:  2006-04-26       Impact factor: 15.419

Review 5.  Biological Activities of Essential Oils: From Plant Chemoecology to Traditional Healing Systems.

Authors:  Javad Sharifi-Rad; Antoni Sureda; Gian Carlo Tenore; Maria Daglia; Mehdi Sharifi-Rad; Marco Valussi; Rosa Tundis; Marzieh Sharifi-Rad; Monica R Loizzo; Adedayo Oluwaseun Ademiluyi; Razieh Sharifi-Rad; Seyed Abdulmajid Ayatollahi; Marcello Iriti
Journal:  Molecules       Date:  2017-01-01       Impact factor: 4.411

6.  Diversity of the volatile organic compounds emitted by 55 species of tropical trees: a survey in French Guiana.

Authors:  Elodie A Courtois; C E Timothy Paine; Pierre-Alain Blandinieres; Didier Stien; Jean-Marie Bessiere; Emeline Houel; Christopher Baraloto; Jerome Chave
Journal:  J Chem Ecol       Date:  2009-12-12       Impact factor: 2.626

7.  Using jasplakinolide to turn on pathways that enable the isolation of new chaetoglobosins from Phomospis asparagi.

Authors:  Omar E Christian; Jennifer Compton; Keisha R Christian; Susan L Mooberry; Fredrick A Valeriote; Phillip Crews
Journal:  J Nat Prod       Date:  2005-11       Impact factor: 4.050

Review 8.  Diversifying carotenoid biosynthetic pathways by directed evolution.

Authors:  Daisuke Umeno; Alexander V Tobias; Frances H Arnold
Journal:  Microbiol Mol Biol Rev       Date:  2005-03       Impact factor: 11.056

9.  Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering.

Authors:  Dana Morrone; Luke Lowry; Mara K Determan; David M Hershey; Meimei Xu; Reuben J Peters
Journal:  Appl Microbiol Biotechnol       Date:  2009-09-24       Impact factor: 4.813

10.  Biosynthesis of ubiquinone compounds with conjugated prenyl side chains.

Authors:  Pyung Cheon Lee; Christine Salomon; Benjamin Mijts; Claudia Schmidt-Dannert
Journal:  Appl Environ Microbiol       Date:  2008-09-26       Impact factor: 4.792
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