Literature DB >> 12957621

Molecular prognostics in colorectal cancer.

Morton S Kahlenberg1, John M Sullivan, Diana Dickson Witmer, Nicholas J Petrelli.   

Abstract

Conventional staging of colorectal cancer does not account for the marked variability in outcome that exists within each stage. Certain populations of patients with early recurrence, resistance to chemotherapy and decreased survival cannot be predicted utilizing common histopathologic criteria. As the molecular mechanisms underlying colorectal carcinogenesis are elucidated, putative molecular prognostic factors are identified. A comprehensive review of various molecular markers and their roles as prognostic factors in colorectal cancer is presented.

Entities:  

Mesh:

Year:  2003        PMID: 12957621     DOI: 10.1016/s0960-7404(03)00006-9

Source DB:  PubMed          Journal:  Surg Oncol        ISSN: 0960-7404            Impact factor:   3.279


  12 in total

1.  Metastatic recurrence of early-stage colorectal cancer is linked to loss of heterozygosity on chromosomes 4 and 14q.

Authors:  F Al-Mulla; S AlFadhli; A H Al-Hakim; J J Going; M S Bitar
Journal:  J Clin Pathol       Date:  2006-06       Impact factor: 3.411

Review 2.  A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy.

Authors:  Vanessa Deschoolmeester; Marc Baay; Pol Specenier; Filip Lardon; Jan B Vermorken
Journal:  Oncologist       Date:  2010-06-28

Review 3.  [Current status of the prognostic value of molecular markers in patients with colorectal cancer and the prediction of response to adjuvant therapy].

Authors:  Jose M Fernández-Cebrián; Peter Vorwald Kuborn; Mar Pardo de Lama; Alfonso Sanjuanbenito Dehesa; Manuel Nevado Santos; Pedro A Pacheco Martínez; Beatriz Fernández-Escudero
Journal:  Clin Transl Oncol       Date:  2005-04       Impact factor: 3.405

4.  Expression of protein S100A4 is a predictor of recurrence in colorectal cancer.

Authors:  Jung-Myun Kwak; Hyun-Joo Lee; Seon-Hahn Kim; Han-Kyeom Kim; Young-Jae Mok; Young-Tae Park; Jong-Sang Choi; Hong-Young Moon
Journal:  World J Gastroenterol       Date:  2010-08-21       Impact factor: 5.742

Review 5.  Predictive and prognostic biomarkers with therapeutic targets in advanced colorectal cancer.

Authors:  Hui-Yan Luo; Rui-Hua Xu
Journal:  World J Gastroenterol       Date:  2014-04-14       Impact factor: 5.742

6.  Specific activity of cyclin-dependent kinase I is a new potential predictor of tumour recurrence in stage II colon cancer.

Authors:  E C M Zeestraten; M Maak; M Shibayama; T Schuster; U Nitsche; T Matsushima; S Nakayama; K Gohda; H Friess; C J H van de Velde; H Ishihara; R Rosenberg; P J K Kuppen; K-P Janssen
Journal:  Br J Cancer       Date:  2011-11-22       Impact factor: 7.640

Review 7.  The prognostic value of the apoptosis pathway in colorectal cancer: a review of the literature on biomarkers identified by immunohistochemistry.

Authors:  Eliane C M Zeestraten; Anne Benard; Marlies S Reimers; Philip C Schouten; Gerrit J Liefers; Cornelis J H van de Velde; Peter J K Kuppen
Journal:  Biomark Cancer       Date:  2013-07-04

8.  Biomarkers in precision therapy in colorectal cancer.

Authors:  Marlies S Reimers; Eliane C M Zeestraten; Peter J K Kuppen; Gerrit Jan Liefers; Cornelis J H van de Velde
Journal:  Gastroenterol Rep (Oxf)       Date:  2013-08-23

Review 9.  Angiogenesis factors involved in the pathogenesis of colorectal cancer.

Authors:  A Mihalache; I Rogoveanu
Journal:  Curr Health Sci J       Date:  2013-12-29

10.  Significance of CEA and VEGF as Diagnostic Markers of Colorectal Cancer in Lebanese Patients.

Authors:  Hashem A Dbouk; Ayman Tawil; Fahd Nasr; Loucine Kandakarjian; Raghida Abou-Merhi
Journal:  Open Clin Cancer J       Date:  2007-11-08
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