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Literature DB >> 12952898

Investigating C. elegans development through mosaic analysis.

Abstract

The analysis of genetically mosaic worms, in which some cells carry a wild-type gene and others are homozygous mutant, can reveal where in the animal a gene acts to prevent the appearance of a mutant phenotype. In this primer article, we describe how Caenorhabditis elegans genetic mosaics are generated, identified and analyzed, and we discuss examples in which the analysis of mosaic worms has provided important information about the development of this organism.

Entities: Species

Mesh：

Year: 2003 PMID： 12952898 DOI： 10.1242/dev.00701

Source DB: PubMed Journal: Development ISSN： 0950-1991 Impact factor: 6.868

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Cited

25 in total

1. V-ATPase V1 sector is required for corpse clearance and neurotransmission in Caenorhabditis elegans.

Authors: Glen G Ernstrom; Robby Weimer; Divya R L Pawar; Shigeki Watanabe; Robert J Hobson; David Greenstein; Erik M Jorgensen
Journal: Genetics Date: 2012-03-16 Impact factor: 4.562

2. KIF1A/UNC-104 Transports ATG-9 to Regulate Neurodevelopment and Autophagy at Synapses.

Authors: Andrea K H Stavoe; Sarah E Hill; David H Hall; Daniel A Colón-Ramos
Journal: Dev Cell Date: 2016-07-07 Impact factor: 12.270

Review 3. Introduction to germ cell development in Caenorhabditis elegans.

Authors: Nanette Pazdernik; Tim Schedl
Journal: Adv Exp Med Biol Date: 2013 Impact factor: 2.622

4. Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins.

Authors: Stephen T Armenti; Lauren L Lohmer; David R Sherwood; Jeremy Nance
Journal: Development Date: 2014-11-05 Impact factor: 6.868

5. The Role of pkc-3 and Genetic Suppressors in Caenorhabditis elegans Epithelial Cell Junction Formation.

Authors: José G Montoyo-Rosario; Stephen T Armenti; Yuliya Zilberman; Jeremy Nance
Journal: Genetics Date: 2020-01-31 Impact factor: 4.562

6. The EGR family gene egrh-1 functions non-autonomously in the control of oocyte meiotic maturation and ovulation in C. elegans.

Authors: Lynn M Clary; Peter G Okkema
Journal: Development Date: 2010-09 Impact factor: 6.868

Investigating C. elegans development through mosaic analysis.

1. V-ATPase V1 sector is required for corpse clearance and neurotransmission in Caenorhabditis elegans.

2. KIF1A/UNC-104 Transports ATG-9 to Regulate Neurodevelopment and Autophagy at Synapses.

Review 3. Introduction to germ cell development in Caenorhabditis elegans.

4. Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins.

5. The Role of pkc-3 and Genetic Suppressors in Caenorhabditis elegans Epithelial Cell Junction Formation.

6. The EGR family gene egrh-1 functions non-autonomously in the control of oocyte meiotic maturation and ovulation in C. elegans.

Review 7. The Caenorhabditis elegans Transgenic Toolbox.

8. Stochasticity and stereotypy in the Ciona notochord.

9. Germline transformation of Caenorhabditis elegans by injection.

10. Glia promote local synaptogenesis through UNC-6 (netrin) signaling in C. elegans.