Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 cAMP signaling in Dictyostelium. Complexity of cAMP synthesis, degradation and detection.

Literature DB >> 12952077

cAMP signaling in Dictyostelium. Complexity of cAMP synthesis, degradation and detection.

Shweta Saran¹, Marcel E Meima, Elisa Alvarez-Curto, Karin E Weening, Daniel E Rozen, Pauline Schaap.

Abstract

cAMP plays a pivotal role in control of cell movement, differentiation and response to stress in all phases of the Dictyostelium life cycle. The multitudinous functions of cAMP require precise spatial and temporal control of its production, degradation and detection. Many novel proteins have recently been identified that critically modulate the cAMP signal. We focus in this review on the properties and functions of the three adenylyl cyclases and the three cAMP-phosphodiesterases that are present in Dictyostelium, and the network of proteins that regulate the activity of these enzymes. We also briefly discuss the two modes of detection of cAMP.

Entities: Chemical

Mesh：

Substances：

Year: 2002 PMID： 12952077 DOI： 10.1023/a:1024483829878

Source DB: PubMed Journal: J Muscle Res Cell Motil ISSN： 0142-4319 Impact factor: 2.698

116 in total

Review 1. Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.

Authors: Celine Mehats; Carsten B Andersen; Marcello Filopanti; S L Catherine Jin; Marco Conti
Journal: Trends Endocrinol Metab Date: 2002 Jan-Feb Impact factor: 12.015

2. Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae.

Authors: J Nikawa; P Sass; M Wigler
Journal: Mol Cell Biol Date: 1987-10 Impact factor: 4.272

3. A developmentally regulated and cAMP-repressible gene of Dictyostelium discoideum: cloning and expression of the gene encoding cyclic nucleotide phosphodiesterase inhibitor.

Authors: L Wu; J Franke
Journal: Gene Date: 1990-07-02 Impact factor: 3.688

Review 4. G protein-coupled receptor adaptation mechanisms.

Authors: S S Ferguson; M G Caron
Journal: Semin Cell Dev Biol Date: 1998-04 Impact factor: 7.727

5. Regulation and function of G alpha protein subunits in Dictyostelium.

Authors: A Kumagai; M Pupillo; R Gundersen; R Miake-Lye; P N Devreotes; R A Firtel
Journal: Cell Date: 1989-04-21 Impact factor: 41.582

6. Regulation of extracellular cyclic-AMP-phosphodiesterase activity during development of Dictyostelium discoideum.

Authors: V Riedel; G Gerisch
Journal: Biochem Biophys Res Commun Date: 1971-01-08 Impact factor: 3.575

7. Role for YakA, cAMP, and protein kinase A in regulation of stress responses of Dictyostelium discoideum cells.

Authors: Alexandre Taminato; Raquel Bagattini; Renata Gorjão; Guokai Chen; Adam Kuspa; Glaucia Mendes Souza
Journal: Mol Biol Cell Date: 2002-07 Impact factor: 4.138

8. A transcriptional profile of multicellular development in Dictyostelium discoideum.

Authors: Nancy Van Driessche; Chad Shaw; Mariko Katoh; Takahiro Morio; Richard Sucgang; Miroslava Ibarra; Hidekazu Kuwayama; Tamao Saito; Hideko Urushihara; Mineko Maeda; Ikuo Takeuchi; Hiroshi Ochiai; William Eaton; Jeffrey Tollett; John Halter; Adam Kuspa; Yoshimasa Tanaka; Gad Shaulsky
Journal: Development Date: 2002-04 Impact factor: 6.868

9. CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium.

Authors: R Insall; A Kuspa; P J Lilly; G Shaulsky; L R Levin; W F Loomis; P Devreotes
Journal: J Cell Biol Date: 1994-09 Impact factor: 10.539

10. The G protein beta subunit is essential for multiple responses to chemoattractants in Dictyostelium.

Authors: L Wu; R Valkema; P J Van Haastert; P N Devreotes
Journal: J Cell Biol Date: 1995-06 Impact factor: 10.539

38 in total

1. Adenylyl cyclase localization to the uropod of aggregating Dictyostelium cells requires RacC.

Authors: C Wang; D Jung; Z Cao; C Y Chung
Journal: Biochem Biophys Res Commun Date: 2015-08-24 Impact factor: 3.575

2. Intracellular role of adenylyl cyclase in regulation of lateral pseudopod formation during Dictyostelium chemotaxis.

Authors: Vesna Stepanovic; Deborah Wessels; Karla Daniels; William F Loomis; David R Soll
Journal: Eukaryot Cell Date: 2005-04

3. A chemoattractant-mediated Gi-coupled pathway activates adenylyl cyclase in human neutrophils.

Authors: Dana C Mahadeo; Mirkka Janka-Junttila; Rory L Smoot; Pavla Roselova; Carole A Parent
Journal: Mol Biol Cell Date: 2006-11-29 Impact factor: 4.138

Review 4. Diverse and dynamic sources and sinks in gradient formation and directed migration.

Authors: Danfeng Cai; Denise J Montell
Journal: Curr Opin Cell Biol Date: 2014-07-12 Impact factor: 8.382

5. BzpF is a CREB-like transcription factor that regulates spore maturation and stability in Dictyostelium.

Authors: Eryong Huang; Shaheynoor Talukder; Timothy R Hughes; Tomaz Curk; Blaz Zupan; Gad Shaulsky; Mariko Katoh-Kurasawa
Journal: Dev Biol Date: 2011-07-23 Impact factor: 3.582

6. Seven Dictyostelium discoideum phosphodiesterases degrade three pools of cAMP and cGMP.

Authors: Sonya Bader; Arjan Kortholt; Peter J M Van Haastert
Journal: Biochem J Date: 2007-02-15 Impact factor: 3.857

7. EppA, a putative substrate of DdERK2, regulates cyclic AMP relay and chemotaxis in Dictyostelium discoideum.

Authors: Songyang Chen; Jeffrey E Segall
Journal: Eukaryot Cell Date: 2006-07

8. The Dictyostelium discoideum acaA gene is transcribed from alternative promoters during aggregation and multicellular development.

Authors: Maria Galardi-Castilla; Ane Garciandía; Teresa Suarez; Leandro Sastre
Journal: PLoS One Date: 2010-10-11 Impact factor: 3.240

9. Transcription profiling of cyclic AMP signaling in Candida albicans.

Authors: Doreen Harcus; André Nantel; Anne Marcil; Tracey Rigby; Malcolm Whiteway
Journal: Mol Biol Cell Date: 2004-07-21 Impact factor: 4.138

10. miR-8 microRNAs regulate the response to osmotic stress in zebrafish embryos.

Authors: Alex S Flynt; Elizabeth J Thatcher; Kristopher Burkewitz; Nan Li; Yinzi Liu; James G Patton
Journal: J Cell Biol Date: 2009-03-30 Impact factor: 10.539