Literature DB >> 12951569

The development and regulation of gene repair.

Li Liu1, Hetal Parekh-Olmedo, Eric B Kmiec.   

Abstract

A technique that can direct the repair of a genetic mutation in a human chromosome using the DNA repair machinery of the cell is under development. Although this approach is not as mature as other forms of gene therapy and fundamental problems continue to arise, it promises to be the ultimate therapy for many inherited disorders. There is a continuing effort to understand the potential and the limitations of this controversial approach.

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Year:  2003        PMID： 12951569     DOI： 10.1038/nrg1156

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN： 1471-0056            Impact factor:   53.242


  21 in total

1.  Multiple roles for MSH2 in the repair of a deletion mutation directed by modified single-stranded oligonucleotides.

Authors:  Katie Kennedy Maguire; Eric B Kmiec
Journal:  Gene       Date:  2006-08-26       Impact factor: 3.688

2.  Buffering of crucial functions by paleologous duplicated genes may contribute cyclicality to angiosperm genome duplication.

Authors:  Brad A Chapman; John E Bowers; Frank A Feltus; Andrew H Paterson
Journal:  Proc Natl Acad Sci U S A       Date:  2006-02-08       Impact factor: 11.205

3.  Reaction parameters of targeted gene repair in mammalian cells.

Authors:  Yiling Hu; Hetal Parekh-Olmedo; Miya Drury; Michael Skogen; Eric B Kmiec
Journal:  Mol Biotechnol       Date:  2005-03       Impact factor: 2.695

4.  Site-specific base changes in the coding or promoter region of the human beta- and gamma-globin genes by single-stranded oligonucleotides.

Authors:  Wenxuan Yin; Betsy T Kren; Clifford J Steer
Journal:  Biochem J       Date:  2005-08-15       Impact factor: 3.857

5.  Increased efficiency of oligonucleotide-mediated gene repair through slowing replication fork progression.

Authors:  Xue-Song Wu; Li Xin; Wen-Xuan Yin; Xi-Ying Shang; Lu Lu; Rory M Watt; Kathryn S E Cheah; Jian-Dong Huang; De-Pei Liu; Chih-Chuan Liang
Journal:  Proc Natl Acad Sci U S A       Date:  2005-02-04       Impact factor: 11.205

6.  Genetic re-engineering of Saccharomyces cerevisiae RAD51 leads to a significant increase in the frequency of gene repair in vivo.

Authors:  Li Liu; Katie K Maguire; Eric B Kmiec
Journal:  Nucleic Acids Res       Date:  2004-04-15       Impact factor: 16.971

Review 7.  Cftr gene targeting in mouse embryonic stem cells mediated by Small Fragment Homologous Replacement (SFHR).

Authors:  Federica Sangiuolo; Maria Lucia Scaldaferri; Antonio Filareto; Paola Spitalieri; Lorenzo Guerra; Maria Favia; Rosa Caroppo; Ruggiero Mango; Emanuela Bruscia; Dieter C Gruenert; Valeria Casavola; Massimo De Felici; Giuseppe Novelli
Journal:  Front Biosci       Date:  2008-01-01

8.  Oligonucleotide delivery by nucleofection does not rescue the reduced proliferation phenotype of gene-edited cells.

Authors:  Paula Livingston; Bryan Strouse; Haley Perry; Mandula Borjigin; Pawel Bialk; Eric B Kmiec
Journal:  Nucleic Acid Ther       Date:  2012-10-16       Impact factor: 5.486

Review 9.  State-of-the-art 2003 on PKU gene therapy.

Authors:  Zhaobing Ding; Cary O Harding; Beat Thöny
Journal:  Mol Genet Metab       Date:  2004-01       Impact factor: 4.797

10.  Camptothecin enhances the frequency of oligonucleotide-directed gene repair in mammalian cells by inducing DNA damage and activating homologous recombination.

Authors:  Luciana Ferrara; Eric B Kmiec
Journal:  Nucleic Acids Res       Date:  2004-10-05       Impact factor: 16.971
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