| Literature DB >> 12951103 |
Yun He1, Baogen Wu, Jun Yang, Dale Robinson, Lisa Risen, Ray Ranken, Lawrence Blyn, Suzie Sheng, Eric E Swayze.
Abstract
A series of 2-piperidin-4-yl-benzimidazoles were synthesized and evaluated for antibacterial activities. Certain compounds inhibit bacterial growth with low micromolar minimal inhibitory concentration (MIC). These benzimidazoles are effective against both Gram-positive and Gram-negative bacteria of clinical importance, particularly enterococci, and represent a new class of potential antibacterial agents.Entities:
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Year: 2003 PMID： 12951103 DOI： 10.1016/s0960-894x(03)00661-9
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823