Literature DB >> 12951094

The stability of pseudopeptides bearing sulfoximines as chiral backbone modifying element towards proteinase K.

Carsten Bolm1, Dirk Müller, Christian Dalhoff, Christian P R Hackenberger, Elmar Weinhold.   

Abstract

Incorporation of sulfoximines as backbone modifying element results in two new pseudopeptide bonds which display enhanced (bond A) and strongly reduced reactivity (bond B) towards hydrolysis by Proteinase K.

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Year:  2003        PMID： 12951094     DOI： 10.1016/s0960-894x(03)00697-8

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation.

Authors:  Alec H Christian; Shang Jia; Wendy Cao; Patricia Zhang; Arismel Tena Meza; Matthew S Sigman; Christopher J Chang; F Dean Toste
Journal:  J Am Chem Soc       Date:  2019-07-30       Impact factor: 15.419

2.  Synthesis of chiral sulfoximine-based thioureas and their application in asymmetric organocatalysis.

Authors:  Marcus Frings; Isabelle Thomé; Carsten Bolm
Journal:  Beilstein J Org Chem       Date:  2012-09-03       Impact factor: 2.883

3.  Modern Stereoselective Synthesis of Chiral Sulfinyl Compounds.

Authors:  Elżbieta Wojaczyńska; Jacek Wojaczyński
Journal:  Chem Rev       Date:  2020-04-29       Impact factor: 60.622

4.  The use of chiral lithium amides in the desymmetrisation of N-trialkylsilyl dimethyl sulfoximines.

Authors:  Matthew J McGrath; Carsten Bolm
Journal:  Beilstein J Org Chem       Date:  2007-10-16       Impact factor: 2.883
  4 in total

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