Literature DB >> 12933894

Long-term protective immune response elicited by vaccination with an expression genomic library of Toxoplasma gondii.

Alberto Fachado1, Alexandro Rodriguez, Judith Molina, Jaline C Silvério, Ana P M P Marino, Luzia M O Pinto, Sergio O Angel, Juan F Infante, Yara Traub-Cseko, Regina R Amendoeira, Joseli Lannes-Vieira.   

Abstract

Immunization of BALB/c mice with an expression genomic library of Toxoplasma gondii induces a Th1-type immune response, with recognition of several T. gondii proteins (21 to 117 kDa) and long-term protective immunity against a lethal challenge. These results support further investigations to achieve a multicomponent anti-T. gondii DNA vaccine.

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Year:  2003        PMID： 12933894      PMCID： PMC187360          DOI： 10.1128/IAI.71.9.5407-5411.2003

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  32 in total

Review 1.  Immune responses to DNA vaccines.

Authors:  D W Kowalczyk; H C Ertl
Journal:  Cell Mol Life Sci       Date:  1999-05       Impact factor: 9.261

2.  Immunization with a DNA plasmid encoding the SAG1 (P30) protein of Toxoplasma gondii is immunogenic and protective in rodents.

Authors:  C W Angus; D Klivington-Evans; J P Dubey; J A Kovacs
Journal:  J Infect Dis       Date:  2000-01       Impact factor: 5.226

3.  Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine.

Authors:  R T Gazzinelli; F T Hakim; S Hieny; G M Shearer; A Sher
Journal:  J Immunol       Date:  1991-01-01       Impact factor: 5.422

Review 4.  Generation of T-cell memory.

Authors:  P C Beverley
Journal:  Curr Opin Immunol       Date:  1996-06       Impact factor: 7.486

5.  Expression library immunization protects mice against a challenge with virulent rodent malaria.

Authors:  P M Smooker; Y Y Setiady; A Rainczuk; T W Spithill
Journal:  Vaccine       Date:  2000-05-22       Impact factor: 3.641

6.  Protective immune responses induced by vaccination with an expression genomic library of Leishmania major.

Authors:  D Piedrafita; D Xu; D Hunter; R A Harrison; F Y Liew
Journal:  J Immunol       Date:  1999-08-01       Impact factor: 5.422

7.  Protective effect of a naked DNA vaccine cocktail against lethal toxoplasmosis in mice.

Authors:  Alberto Fachado; Alexandro Rodriguez; Sergio O Angel; Diamar C Pinto; Iviane Vila; Armando Acosta; Regina R Amendoeira; Joseli Lannes-Vieira
Journal:  Vaccine       Date:  2003-03-28       Impact factor: 3.641

8.  Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts.

Authors:  R T Gazzinelli; S Hieny; T A Wynn; S Wolf; A Sher
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

9.  Toxoplasmosis: the first commercial vaccine.

Authors:  D Buxton
Journal:  Parasitol Today       Date:  1993-09

Review 10.  Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection.

Authors:  E Y Denkers; R T Gazzinelli
Journal:  Clin Microbiol Rev       Date:  1998-10       Impact factor: 26.132
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  3 in total

Review 1.  Expression library immunization: a road map for discovery of vaccines against infectious diseases.

Authors:  Adel M Talaat; Katherine Stemke-Hale
Journal:  Infect Immun       Date:  2005-11       Impact factor: 3.441

2.  A comparative study between excretory/secretory and autoclaved vaccines against RH strain of Toxoplasma gondii in murine models.

Authors:  Hayam Mohamed Ezz Eldin; Hanan Hussein Kamel; Abeer Fathy Badawy; Lobna Sadek Shash
Journal:  J Parasit Dis       Date:  2013-11-20

3.  Vesicular Stomatitis Virus-Vectored Multi-Antigen Tuberculosis Vaccine Limits Bacterial Proliferation in Mice following a Single Intranasal Dose.

Authors:  Ming Zhang; Chunsheng Dong; Sidong Xiong
Journal:  Front Cell Infect Microbiol       Date:  2017-02-07       Impact factor: 5.293
  3 in total

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