Literature DB >> 12932641

Micelles from polyethylene glycol/phosphatidylethanolamine conjugates for tumor drug delivery.

Anatoly N Lukyanov1, Zhonggao Gao, Vladimir P Torchilin.   

Abstract

Micelles prepared from polyethylene glycols of various lengths conjugated with phosphatidylethanolamine (PEG-PE) were loaded with various poorly soluble anticancer agents. PEG-PE micelles selectively accumulated in Lewis lung carcinoma (LLC) tumors implanted in mice. Modification of the micelles with tumor specific antibodies further enhanced the efficiency of tumor accumulation.

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Year:  2003        PMID： 12932641     DOI： 10.1016/s0168-3659(03)00217-7

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


  21 in total

1.  An assessment of the effects of shell cross-linked nanoparticle size, core composition, and surface PEGylation on in vivo biodistribution.

Authors:  Xiankai Sun; Raffaella Rossin; Jeffrey L Turner; Matthew L Becker; Maisie J Joralemon; Michael J Welch; Karen L Wooley
Journal:  Biomacromolecules       Date:  2005 Sep-Oct       Impact factor: 6.988

2.  Polymeric micelles of PEG-PE as carriers of all-trans retinoic acid for stability improvement.

Authors:  Angkana Wichit; Anothai Tangsumranjit; Tasana Pitaksuteepong; Neti Waranuch
Journal:  AAPS PharmSciTech       Date:  2012-01-25       Impact factor: 3.246

Review 3.  Polymer architecture and drug delivery.

Authors:  Li Yan Qiu; You Han Bae
Journal:  Pharm Res       Date:  2006-01-11       Impact factor: 4.200

4.  Targeting of Micelles and Liposomes Loaded with the Pro-Apoptotic Drug, NCL-240, into NCI/ADR-RES Cells in a 3D Spheroid Model.

Authors:  Bhushan S Pattni; Srikar G Nagelli; Bhawani Aryasomayajula; Pranali P Deshpande; Abhijit Kulkarni; William C Hartner; Ganesh Thakur; Alexei Degterev; Vladimir P Torchilin
Journal:  Pharm Res       Date:  2016-06-28       Impact factor: 4.200

5.  Polyethylene glycol-phosphatidylethanolamine (PEG-PE)/vitamin E micelles for co-delivery of paclitaxel and curcumin to overcome multi-drug resistance in ovarian cancer.

Authors:  Abraham H Abouzeid; Niravkumar R Patel; Vladimir P Torchilin
Journal:  Int J Pharm       Date:  2014-01-17       Impact factor: 5.875

Review 6.  Drug delivery trends in clinical trials and translational medicine: challenges and opportunities in the delivery of nucleic acid-based therapeutics.

Authors:  Long Xu; Thomas Anchordoquy
Journal:  J Pharm Sci       Date:  2011-01       Impact factor: 3.534

7.  Tyrosine polyethylene glycol (PEG)-micelle magnetic resonance contrast agent for the detection of lipid rich areas in atherosclerotic plaque.

Authors:  Anne Beilvert; David P Cormode; Frédéric Chaubet; Karen C Briley-Saebo; Venkatesh Mani; Willem J M Mulder; Esad Vucic; Jean-François Toussaint; Didier Letourneur; Zahi A Fayad
Journal:  Magn Reson Med       Date:  2009-11       Impact factor: 4.668

8.  Environment-Responsive Polymers for Coating of Pharmaceutical Nanocarriers(,).

Authors:  A A Kale; V P Torchilin
Journal:  Polym Sci Ser A Chem Phys       Date:  2009-06

9.  Mixed PEG-PE/vitamin E tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: improved drug solubilization and enhanced in vitro cytotoxicity.

Authors:  Rupa R Sawant; Rishikesh M Sawant; Vladimir P Torchilin
Journal:  Eur J Pharm Biopharm       Date:  2008-04-29       Impact factor: 5.571

10.  PEG-PE micelles loaded with paclitaxel and surface-modified by a PBR-ligand: synergistic anticancer effect.

Authors:  Tiziana Musacchio; Valentino Laquintana; Andrea Latrofa; Giuseppe Trapani; Vladimir P Torchilin
Journal:  Mol Pharm       Date:  2009 Mar-Apr       Impact factor: 4.939
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