Literature DB >> 12930852

Extending preimplantation genetic diagnosis: medical and non-medical uses.

J A Robertson1.   

Abstract

New uses of preimplantation genetic diagnosis (PGD) to screen embryos prior to transfer raise ethical, legal, and policy issues that deserve close attention. Extensions for medical purposes, such as to identify susceptibility genes, late onset disease, and human leukocyte antigen (HLA) matching, are usually ethically acceptable. Whether embryo screening for gender, perfect pitch, or other non-medical characteristics are also acceptable depends upon the parental needs served and the harm posed to embryos, children, and society. Speculations about potential future uses of PGD should not prevent otherwise acceptable current uses of PGD.

Entities:  

Keywords:  Genetics and Reproduction

Mesh:

Year:  2003        PMID: 12930852      PMCID: PMC1733767          DOI: 10.1136/jme.29.4.213

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  10 in total

1.  Preimplantation sex selection for family balancing in India.

Authors:  A Malpani; A Malpani; D Modi
Journal:  Hum Reprod       Date:  2002-01       Impact factor: 6.918

2.  Ethics of preimplantation diagnosis for a woman destined to develop early-onset Alzheimer disease.

Authors:  Dena Towner; Roberta Springer Loewy
Journal:  JAMA       Date:  2002-02-27       Impact factor: 56.272

Review 3.  Preconception gender selection.

Authors:  J A Robertson
Journal:  Am J Bioeth       Date:  2001       Impact factor: 11.229

4.  Conception to obtain hematopoietic stem cells.

Authors:  John A Robertson; Jeffrey P Kahn; John E Wagner
Journal:  Hastings Cent Rep       Date:  2002 May-Jun       Impact factor: 2.683

5.  Celebrating preimplantation genetic diagnosis of p53 mutations in Li-Fraumeni syndrome.

Authors:  Joe Leigh Simpson
Journal:  Reprod Biomed Online       Date:  2001       Impact factor: 3.828

6.  Sex selection for gender variety by preimplantation genetic diagnosis.

Authors:  John A Robertson
Journal:  Fertil Steril       Date:  2002-09       Impact factor: 7.329

7.  Preimplantation diagnosis for Fanconi anemia combined with HLA matching.

Authors:  Y Verlinsky; S Rechitsky; W Schoolcraft; C Strom; A Kuliev
Journal:  JAMA       Date:  2001-06-27       Impact factor: 56.272

8.  Preimplantation diagnosis for early-onset Alzheimer disease caused by V717L mutation.

Authors:  Yury Verlinsky; Svetlana Rechitsky; Oleg Verlinsky; Christina Masciangelo; Kevin Lederer; Anver Kuliev
Journal:  JAMA       Date:  2002-02-27       Impact factor: 56.272

Review 9.  Ethical considerations on preimplantation genetic diagnosis for HLA typing to match a future child as a donor of haematopoietic stem cells to a sibling.

Authors:  G Pennings; R Schots; I Liebaers
Journal:  Hum Reprod       Date:  2002-03       Impact factor: 6.918

10.  Preimplantation diagnosis for p53 tumour suppressor gene mutations.

Authors:  Yury Verlinsky; Svetlana Rechitsky; Oleg Verlinsky; Kangu Xu; Glenn Schattman; Christina Masciangelo; Norman Ginberg; Charles Strom; Zev Rosenwaks; Anver Kuliev
Journal:  Reprod Biomed Online       Date:  2001       Impact factor: 3.828

  10 in total
  3 in total

1.  Bach to the future: response to: Extending preimplantation genetic diagnosis: medical and non-medical uses.

Authors:  R Ashcroft
Journal:  J Med Ethics       Date:  2003-08       Impact factor: 2.903

2.  Preimplantation genetic diagnosis: does age of onset matter (anymore)?

Authors:  Timothy Krahn
Journal:  Med Health Care Philos       Date:  2008-11-01

3.  Attitudes to reproductive genetic testing in women who had a positive BRCA test before having children: a qualitative analysis.

Authors:  Elizabeth Ormondroyd; Louise Donnelly; Clare Moynihan; Cornelie Savona; Elizabeth Bancroft; D Gareth Evans; Rosalind Eeles; Stuart Lavery; Maggie Watson
Journal:  Eur J Hum Genet       Date:  2011-08-03       Impact factor: 4.246

  3 in total

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