Literature DB >> 12930510

Flecainide induced ventricular tachycardia (torsades de pointes).

Jerome Thevenin1, Antoine Da Costa, Frederic Roche, Cecile Romeyer, Marc Messier, Karl Isaaz.   

Abstract

This case report describes a 68-year-old woman presenting with flecainide induced syncope due to torsades de pointes (TP) ventricular tachycardia. Before TP onset, the QTc interval reached 680 ms without changes in QRS duration. None of the usual triggers were found. Prolongation of QT under flecaïnide is exceptional and the occurrence of TP without concurrent triggers has not been reported in the literature.

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Year:  2003        PMID: 12930510     DOI: 10.1046/j.1460-9592.2003.00290.x

Source DB:  PubMed          Journal:  Pacing Clin Electrophysiol        ISSN: 0147-8389            Impact factor:   1.976


  5 in total

1.  Acquired long QT syndrome and ventricular tachycardia in a patient on flecainide therapy.

Authors:  Chang-Woo Son; Sang-Hee Lee; Dong-Gu Shin; Gue-Ru Hong; Jong-Seon Park
Journal:  J Cardiol Cases       Date:  2011-03-29

2.  Pharmacokinetic interaction of flecainide and paroxetine in relation to the CYP2D6*10 allele in healthy Korean subjects.

Authors:  Kyoung Soo Lim; Joo-Youn Cho; In-Jin Jang; Bo-Hyung Kim; JaeWoo Kim; Ji-Young Jeon; Yu-Mi Tae; SoJeong Yi; SoYoung Eum; Sang-Goo Shin; Kyung-Sang Yu
Journal:  Br J Clin Pharmacol       Date:  2008-07-24       Impact factor: 4.335

Review 3.  [Drug induced QT prolongation].

Authors:  David Altmann; Urs Eggmann; Peter Ammann
Journal:  Wien Klin Wochenschr       Date:  2008       Impact factor: 1.704

4.  Molecular basis of hERG potassium channel blockade by the class Ic antiarrhythmic flecainide.

Authors:  Dario Melgari; Yihong Zhang; Aziza El Harchi; Christopher E Dempsey; Jules C Hancox
Journal:  J Mol Cell Cardiol       Date:  2015-07-06       Impact factor: 5.000

5.  Torsades de Pointes associated with QT prolongation after catheter ablation of paroxysmal atrial fibrillation.

Authors:  Yae Min Park; Mi Suk Cha; Woong Chol Kang; Mi-Seung Shin; Young-Hoon Kim; In Suck Choi; Eak Kyun Shin
Journal:  Indian Pacing Electrophysiol J       Date:  2017-07-13
  5 in total

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