Literature DB >> 12929379

HIV-1 protease: mechanism and drug discovery.

Ashraf Brik1, Chi-Huey Wong.   

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Year:  2003        PMID： 12929379     DOI： 10.1039/b208248a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


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  94 in total

1.  A force field with discrete displaceable waters and desolvation entropy for hydrated ligand docking.

Authors:  Stefano Forli; Arthur J Olson
Journal:  J Med Chem       Date:  2012-01-13       Impact factor: 7.446

2.  Small molecules targeting severe acute respiratory syndrome human coronavirus.

Authors:  Chung-Yi Wu; Jia-Tsrong Jan; Shiou-Hwa Ma; Chih-Jung Kuo; Hsueh-Fen Juan; Yih-Shyun E Cheng; Hsien-Hua Hsu; Hsuan-Cheng Huang; Douglass Wu; Ashraf Brik; Fu-Sen Liang; Rai-Shung Liu; Jim-Min Fang; Shui-Tein Chen; Po-Huang Liang; Chi-Huey Wong
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-28       Impact factor: 11.205

3.  Transition states of native and drug-resistant HIV-1 protease are the same.

Authors:  D Randal Kipp; Jennifer S Hirschi; Aya Wakata; Harris Goldstein; Vern L Schramm
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-09       Impact factor: 11.205

4.  Intramolecular regulation of the sequence-specific mRNA interferase activity of MazF fused to a MazE fragment with a linker cleavable by specific proteases.

Authors:  Jung-Ho Park; Yoshihiro Yamaguchi; Masayori Inouye
Journal:  Appl Environ Microbiol       Date:  2012-03-23       Impact factor: 4.792

5.  Strategies for assessing proton linkage to bimolecular interactions by global analysis of isothermal titration calorimetry data.

Authors:  Nathan P Coussens; Peter Schuck; Huaying Zhao
Journal:  J Chem Thermodyn       Date:  2012-09-01       Impact factor: 3.178

6.  Synthetic, structural mimetics of the β-hairpin flap of HIV-1 protease inhibit enzyme function.

Authors:  Jay Chauhan; Shen-En Chen; Katherine J Fenstermacher; Aurash Naser-Tavakolian; Tali Reingewertz; Rosene Salmo; Christian Lee; Emori Williams; Mithun Raje; Eric Sundberg; Jeffrey J DeStefano; Ernesto Freire; Steven Fletcher
Journal:  Bioorg Med Chem       Date:  2015-09-07       Impact factor: 3.641

Review 7.  Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS.

Authors:  Arun K Ghosh; Heather L Osswald; Gary Prato
Journal:  J Med Chem       Date:  2016-01-22       Impact factor: 7.446

8.  How similar are enzyme active site geometries derived from quantum mechanical theozymes to crystal structures of enzyme-inhibitor complexes? Implications for enzyme design.

Authors:  Jason Dechancie; Fernando R Clemente; Adam J T Smith; Hakan Gunaydin; Yi-Lei Zhao; Xiyun Zhang; K N Houk
Journal:  Protein Sci       Date:  2007-09       Impact factor: 6.725

9.  Crystallization and preliminary neutron diffraction studies of HIV-1 protease cocrystallized with inhibitor KNI-272.

Authors:  Hiroyoshi Matsumura; Motoyasu Adachi; Shigeru Sugiyama; Shino Okada; Megumi Yamakami; Taro Tamada; Koushi Hidaka; Yoshio Hayashi; Tooru Kimura; Yoshiaki Kiso; Tomoya Kitatani; Sho Maki; Hiroshi Y Yoshikawa; Hiroaki Adachi; Kazufumi Takano; Satoshi Murakami; Tsuyoshi Inoue; Ryota Kuroki; Yusuke Mori
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2008-10-25

10.  Design and Synthesis of Potent HIV-1 Protease Inhibitors Containing Bicyclic Oxazolidinone Scaffold as the P2 Ligands: Structure-Activity Studies and Biological and X-ray Structural Studies.

Authors:  Arun K Ghosh; Jacqueline N Williams; Rachel Y Ho; Hannah M Simpson; Shin-Ichiro Hattori; Hironori Hayashi; Johnson Agniswamy; Yuan-Fang Wang; Irene T Weber; Hiroaki Mitsuya
Journal:  J Med Chem       Date:  2018-10-24       Impact factor: 7.446
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