Literature DB >> 12927951

Effect of siliconized latex urinary catheters on the activity of carbapenems against Pseudomonas aeruginosa strains with defined mutations in ampC, oprD, and genes coding for efflux systems.

M Carmen Conejo1, Luis Martínez-Martínez, Isabel García, Leandro Picabea, Alvaro Pascual.   

Abstract

The decreased activity of carbapenems against Pseudomonas aeruginosa in the presence of eluates from siliconized latex urinary catheters is related to the loss of OprD and the expression of a new outer membrane protein (OMP). To understand this phenomenon, the activity of carbapenems and quinolones against P. aeruginosa strains, some producing AmpC beta-lactamase (BL), OprD, MexA-MexB-OprM and MexE-MexF-OprN, were determined in Mueller-Hinton broth (MH) and in MH-containing eluates. OMP profiles and BL activities were also studied. Resistance to imipenem in P. aeruginosa grown in eluate is due to both the loss of OprD and expression of BL. For meropenem this phenomenon is related to both the loss of OprD and the integrity of MexA-MexB-OprM.

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Year:  2003        PMID： 12927951     DOI： 10.1016/s0924-8579(03)00119-5

Source DB:  PubMed          Journal:  Int J Antimicrob Agents        ISSN： 0924-8579            Impact factor:   5.283


  8 in total

1.  Accumulation of 99mTc-ciprofloxacin in Staphylococcus aureus and Pseudomonas aeruginosa.

Authors:  J M Sierra; D Rodriguez-Puig; A Soriano; J Mensa; C Piera; J Vila
Journal:  Antimicrob Agents Chemother       Date:  2008-05-12       Impact factor: 5.191

2.  Local imipenem activity against Pseudomonas aeruginosa decreases in vivo in the presence of siliconized latex.

Authors:  C Pichardo; M C Conejo; F Docobo-Pérez; C Velasco; R López-Rojas; I García; M E Pachón-Ibáñez; J M Rodríguez; J Pachón; A Pascual
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2010-10-10       Impact factor: 3.267

3.  High-resolution genotyping of Pseudomonas aeruginosa strains linked to acute post cataract surgery endophthalmitis outbreaks in India.

Authors:  Prashanth Kenchappa; Virender S Sangwan; Niyaz Ahmed; K Rajender Rao; Avinash Pathengay; Annie Mathai; Tarannum Mansoori; Taraprasad Das; Seyed E Hasnain; Savitri Sharma
Journal:  Ann Clin Microbiol Antimicrob       Date:  2005-12-12       Impact factor: 3.944

4.  Relation between Resistance to Antipseudomonal β-Lactams and ampC and mexC Genes of Pseudomonas aeruginosa.

Authors:  Fatemeh Rezaei; Horieh Saderi; Shahrsam Boroumandi; Soghrat Faghihzadeh
Journal:  Iran J Pathol       Date:  2016

5.  Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides.

Authors:  Susana Sánchez-Gómez; Marta Lamata; José Leiva; Sylvie E Blondelle; Roman Jerala; Jörg Andrä; Klaus Brandenburg; Karl Lohner; Ignacio Moriyón; Guillermo Martínez-de-Tejada
Journal:  BMC Microbiol       Date:  2008-11-11       Impact factor: 3.605

6.  Detecting and minimizing zinc contamination in physiological solutions.

Authors:  Alan R Kay
Journal:  BMC Physiol       Date:  2004-03-15

7.  A synthetic peptide sensitizes multi-drug resistant Pseudomonas aeruginosa to antibiotics for more than two hours and permeabilizes its envelope for twenty hours.

Authors:  Iosu Rázquin-Olazarán; Hawraa Shahrour; Guillermo Martínez-de-Tejada
Journal:  J Biomed Sci       Date:  2020-08-06       Impact factor: 8.410

8.  A permeability-increasing drug synergizes with bacterial efflux pump inhibitors and restores susceptibility to antibiotics in multi-drug resistant Pseudomonas aeruginosa strains.

Authors:  Raquel Ferrer-Espada; Hawraa Shahrour; Betsey Pitts; Philip S Stewart; Susana Sánchez-Gómez; Guillermo Martínez-de-Tejada
Journal:  Sci Rep       Date:  2019-03-05       Impact factor: 4.379
  8 in total

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