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Literature DB >> 12923109

IS1999 increases expression of the extended-spectrum beta-lactamase VEB-1 in Pseudomonas aeruginosa.

Daniel Aubert¹, Thierry Naas, Patrice Nordmann.

Abstract

The integron-borne bla(VEB-1) gene encodes an extended-spectrum beta-lactamase. This gene was associated mostly with IS1999 and rarely with an additional IS2000 element in Pseudomonas aeruginosa isolates from Thailand, whereas IS1999 was only very rarely associated with bla(VEB-1) in Enterobacteriaceae. Expression experiments and promoter study identified promoter sequences in IS1999 that increased the expression of VEB-1 in P. aeruginosa.

Entities: Gene Species

Mesh：

Substances：

Year: 2003 PMID： 12923109 PMCID： PMC181007 DOI： 10.1128/JB.185.17.5314-5319.2003

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

17 in total

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Journal: J Bacteriol Date: 1991-07 Impact factor: 3.490

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Journal: J Bacteriol Date: 2006-09 Impact factor: 3.490

Review 3. Antimicrobial Resistance in ESKAPE Pathogens.

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Authors: Vanderlene L Kung; Egon A Ozer; Alan R Hauser
Journal: Microbiol Mol Biol Rev Date: 2010-12 Impact factor: 11.056

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6. A family of insertion sequences that impacts integrons by specific targeting of gene cassette recombination sites, the IS1111-attC Group.

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