Literature DB >> 12916088

Antioxidant properties of scopoletin isolated from Sinomonium acutum.

Chin-Ying Shaw1, Chen-Hui Chen, Chih-Chieh Hsu, Chien-Chih Chen, Ying-Chieh Tsai.   

Abstract

Scopoletin was isolated from Sinomonium acutum and studied using four experimental models designed to assess antioxidant properties. The results indicated that scopoletin scavenged superoxide anion in the xanthine/xanthine oxidase reaction system in a concentration-dependent manner, but did not inhibit xanthine oxidase. Scopoletin may therefore be responsible for the superoxide anion scavenging activity seen in Sinomonium acutum extracts and may be of use in preventing superoxide anion-induced damage in vivo. Copyright 2003 John Wiley & Sons, Ltd.

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Year:  2003        PMID: 12916088     DOI: 10.1002/ptr.1170

Source DB:  PubMed          Journal:  Phytother Res        ISSN: 0951-418X            Impact factor:   5.878


  25 in total

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9.  The coumarin scopoletin potentiates acetylcholine release from synaptosomes, amplifies hippocampal long-term potentiation and ameliorates anticholinergic- and age-impaired memory.

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