Literature DB >> 12903346

Condensation reaction of hexanucleotides containing guanine and cytosine with water soluble carbodiimide.

K Kawamura1, F Okamoto.   

Abstract

The condensation reactions of hexanucleotides involving guanine and cytosine in the presence of water-soluble carbodiimide (WSC) have been investigated as a model reaction of the prebiotic formation of RNA under primitive earth. The reactions formed cyclic hexanucleotides and dimers in which the product yields were dependent on the sequence.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 12903346     DOI： 10.1093/nass/44.1.217

Source DB:  PubMed          Journal:  Nucleic Acids Symp Ser        ISSN： 0261-3166


  3 in total

1.  Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world.

Authors:  Eric D Horowitz; Aaron E Engelhart; Michael C Chen; Kaycee A Quarles; Michael W Smith; David G Lynn; Nicholas V Hud
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-08       Impact factor: 11.205

Review 2.  Primitive genetic polymers.

Authors:  Aaron E Engelhart; Nicholas V Hud
Journal:  Cold Spring Harb Perspect Biol       Date:  2010-05-12       Impact factor: 10.005

3.  In situ imidazole activation of ribonucleotides for abiotic RNA oligomerization reactions.

Authors:  Bradley T Burcar; Mohsin Jawed; Hari Shah; Linda B McGown
Journal:  Orig Life Evol Biosph       Date:  2015-02-27       Impact factor: 1.950
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.