Literature DB >> 12902052

Neuropharmacological activity of Nigella sativa L. extracts.

T B Al-Naggar1, M P Gómez-Serranillos, M E Carretero, A M Villar.   

Abstract

Pharmacological studies have been conducted on the aqueous and methanol extracts of defatted Nigella sativa L. seeds to evaluate their effects on the central nervous system (CNS) and on analgesic activity. The observations suggest that the two extracts of Nigella sativa possesses a potent CNS and analgesic activity (depressant action especially in the case of the methanolic extract).

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Year:  2003        PMID： 12902052     DOI： 10.1016/s0378-8741(03)00157-0

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  27 in total

1.  Evaluation of analgesic and anti-inflammatory activity of diospyros cordifolia extract.

Authors:  Sudipta Das; Pallab K Haldar; Goutam Pramanik; Siva P Panda; Samit Bera
Journal:  Afr J Tradit Complement Altern Med       Date:  2010-10-02

2.  Antimalarial and antioxidant activities of methanolic extract of Nigella sativa seeds (black cumin) in mice infected with Plasmodium yoelli nigeriensis.

Authors:  Valeelat O Okeola; Oluwatosin A Adaramoye; Chiaka M Nneji; Catherine O Falade; E Olatunde Farombi; Olusegun G Ademowo
Journal:  Parasitol Res       Date:  2010-12-14       Impact factor: 2.289

3.  Gastroprotective effects of Nigella Sativa oil on the formation of stress gastritis in hypothyroidal rats.

Authors:  Khaled A Abdel-Sater
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2009-03-10

4.  Potentiation of Valproate-induced Anticonvulsant Response by Nigella sativa Seed Constituents: The Role of GABA Receptors.

Authors:  Muhammad Raza; Abdullah A Alghasham; Mohammad S Alorainy; Tarig M El-Hadiyah
Journal:  Int J Health Sci (Qassim)       Date:  2008-01

5.  Nigella sativa L. seed extract modulates the neurotransmitter amino acids release in cultured neurons in vitro.

Authors:  Tarek El-Naggar; María Pilar Gómez-Serranillos; Olga María Palomino; Carmen Arce; María Emilia Carretero
Journal:  J Biomed Biotechnol       Date:  2010-06-16

6.  Effects of Nigella sativa on outcome of hepatitis C in Egypt.

Authors:  Eman Mahmoud Fathy Barakat; Lamia Mohamed El Wakeel; Radwa Samir Hagag
Journal:  World J Gastroenterol       Date:  2013-04-28       Impact factor: 5.742

Review 7.  A review on therapeutic potential of Nigella sativa: A miracle herb.

Authors:  Aftab Ahmad; Asif Husain; Mohd Mujeeb; Shah Alam Khan; Abul Kalam Najmi; Nasir Ali Siddique; Zoheir A Damanhouri; Firoz Anwar
Journal:  Asian Pac J Trop Biomed       Date:  2013-05

8.  Evaluation of the possible epileptogenic activity of ciprofloxacin: the role of Nigella sativa on amino acids neurotransmitters.

Authors:  Nadia M S Arafa; Mona Abdel-Rahman; Manal F El-khadragy; Rami B Kassab
Journal:  Neurochem Res       Date:  2012-10-21       Impact factor: 3.996

9.  Antinociceptive and antiinflammatory effects of essential oil of Dennettia tripetala G.Baker (Annonaceae) in rodents.

Authors:  I A Oyemitan; E O Iwalewa; M A Akanmu; T A Olugbade
Journal:  Afr J Tradit Complement Altern Med       Date:  2008-06-18

10.  Anti-Inflammatory Activity Is a Possible Mechanism by Which the Polyherbal Formulation Comprised of Nigella sativa (Seeds), Hemidesmus indicus (Root), and Smilax glabra (Rhizome) Mediates Its Antihepatocarcinogenic Effects.

Authors:  Prasanna B Galhena; Sameera R Samarakoon; M Ira Thabrew; G A K Weerasinghe; Mayuri G Thammitiyagodage; W D Ratnasooriya; Kamani H Tennekoon
Journal:  Evid Based Complement Alternat Med       Date:  2012-11-13       Impact factor: 2.629
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