Literature DB >> 12897019

A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity.

Mark P Stevens1, Andrea Friebel, Lowrie A Taylor, Michael W Wood, Philip J Brown, Wolf-Dietrich Hardt, Edouard E Galyov.   

Abstract

We report the characterization of BopE, a type III secreted protein that is encoded adjacent to the Burkholderia pseudomallei bsa locus and is homologous to Salmonella enterica SopE/SopE2. Inactivation of bopE impaired bacterial entry into HeLa cells, indicating that BopE facilitates invasion. Consistent with this notion, BopE expressed in eukaryotic cells induced rearrangements in the subcortical actin cytoskeleton, and purified BopE exhibited guanine nucleotide exchange factor activity for Cdc42 and Rac1 in vitro.

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Year:  2003        PMID： 12897019      PMCID： PMC166480          DOI： 10.1128/JB.185.16.4992-4996.2003

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  39 in total

1.  Characterization of the interactions between the small GTPase RhoA and its guanine nucleotide exchange factors.

Authors:  Ying-Cai Tan; Hao Wu; Wei-Ning Wang; Yi Zheng; Zhi-Xin Wang
Journal:  Anal Biochem       Date:  2002-11-15       Impact factor: 3.365

2.  Melioidosis: recrudescence associated with bronchogenic carcinoma twenty-six years following initial geographic exposure.

Authors:  E E Mays; E A Ricketts
Journal:  Chest       Date:  1975-08       Impact factor: 9.410

3.  Phage mediated horizontal transfer of the sopE1 gene increases enteropathogenicity of Salmonella enterica serotype Typhimurium for calves.

Authors:  Shuping Zhang; Renato L Santos; Renée M Tsolis; Susanne Mirold; Wolf-Dietrich Hardt; L Garry Adams; Andreas J Bäumler
Journal:  FEMS Microbiol Lett       Date:  2002-12-17       Impact factor: 2.742

4.  Analysis of intrinsic and CDC25-stimulated guanine nucleotide exchange of p21ras-nucleotide complexes by fluorescence measurements.

Authors:  C Lenzen; R H Cool; A Wittinghofer
Journal:  Methods Enzymol       Date:  1995       Impact factor: 1.600

5.  Intracellular survival of Burkholderia pseudomallei.

Authors:  A L Jones; T J Beveridge; D E Woods
Journal:  Infect Immun       Date:  1996-03       Impact factor: 3.441

6.  Relapse in melioidosis: incidence and risk factors.

Authors:  W Chaowagul; Y Suputtamongkol; D A Dance; A Rajchanuvong; J Pattara-arechachai; N J White
Journal:  J Infect Dis       Date:  1993-11       Impact factor: 5.226

7.  Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.

Authors:  S M Franken; A J Scheidig; U Krengel; H Rensland; A Lautwein; M Geyer; K Scheffzek; R S Goody; H R Kalbitzer; E F Pai
Journal:  Biochemistry       Date:  1993-08-24       Impact factor: 3.162

8.  Identification of two targets of the type III protein secretion system encoded by the inv and spa loci of Salmonella typhimurium that have homology to the Shigella IpaD and IpaA proteins.

Authors:  K Kaniga; D Trollinger; J E Galán
Journal:  J Bacteriol       Date:  1995-12       Impact factor: 3.490

9.  Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using fluorescence spectroscopy.

Authors:  D A Leonard; T Evans; M Hart; R A Cerione; D Manor
Journal:  Biochemistry       Date:  1994-10-11       Impact factor: 3.162

10.  Survival of Pseudomonas pseudomallei in human phagocytes.

Authors:  S Pruksachartvuthi; N Aswapokee; K Thankerngpol
Journal:  J Med Microbiol       Date:  1990-02       Impact factor: 2.472
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  69 in total

Review 1.  Computational prediction of type III and IV secreted effectors in gram-negative bacteria.

Authors:  Jason E McDermott; Abigail Corrigan; Elena Peterson; Christopher Oehmen; George Niemann; Eric D Cambronne; Danna Sharp; Joshua N Adkins; Ram Samudrala; Fred Heffron
Journal:  Infect Immun       Date:  2010-10-25       Impact factor: 3.441

2.  Comparative assessment of the intracellular survival of the Burkholderia pseudomallei bopC mutant.

Authors:  Varintip Srinon; Sunsiree Muangman; Nithima Imyaem; Veerachat Muangsombut; Natalie R Lazar Adler; Edouard E Galyov; Sunee Korbsrisate
Journal:  J Microbiol       Date:  2013-08-30       Impact factor: 3.422

3.  Identification and discrimination of Burkholderia pseudomallei, B. mallei, and B. thailandensis by real-time PCR targeting type III secretion system genes.

Authors:  F M Thibault; E Valade; D R Vidal
Journal:  J Clin Microbiol       Date:  2004-12       Impact factor: 5.948

4.  A type IV pilin, PilA, Contributes To Adherence of Burkholderia pseudomallei and virulence in vivo.

Authors:  Angela E Essex-Lopresti; Justin A Boddey; Richard Thomas; Martin P Smith; M Gill Hartley; Timothy Atkins; Nat F Brown; Chuk Hai Tsang; Ian R A Peak; Jim Hill; Ifor R Beacham; Richard W Titball
Journal:  Infect Immun       Date:  2005-02       Impact factor: 3.441

5.  Multinucleated giant cell formation and apoptosis in infected host cells is mediated by Burkholderia pseudomallei type III secretion protein BipB.

Authors:  Supaporn Suparak; Wannapa Kespichayawattana; Ashraful Haque; Anna Easton; Suwat Damnin; Ganjana Lertmemongkolchai; Gregory J Bancroft; Sunee Korbsrisate
Journal:  J Bacteriol       Date:  2005-09       Impact factor: 3.490

6.  The animal pathogen-like type III secretion system is required for the intracellular survival of Burkholderia mallei within J774.2 macrophages.

Authors:  Wilson J Ribot; Ricky L Ulrich
Journal:  Infect Immun       Date:  2006-07       Impact factor: 3.441

7.  Sensitive and specific molecular detection of Burkholderia pseudomallei, the causative agent of melioidosis, in the soil of tropical northern Australia.

Authors:  Mirjam Kaestli; Mark Mayo; Glenda Harrington; Felicity Watt; Jason Hill; Daniel Gal; Bart J Currie
Journal:  Appl Environ Microbiol       Date:  2007-09-14       Impact factor: 4.792

Review 8.  Role of phages in the pathogenesis of Burkholderia, or 'Where are the toxin genes in Burkholderia phages?'.

Authors:  Elizabeth J Summer; Jason J Gill; Chris Upton; Carlos F Gonzalez; Ry Young
Journal:  Curr Opin Microbiol       Date:  2007-08-23       Impact factor: 7.934

Review 9.  Human Melioidosis.

Authors:  I Gassiep; M Armstrong; R Norton
Journal:  Clin Microbiol Rev       Date:  2020-03-11       Impact factor: 26.132

10.  Regulation of type VI secretion system during Burkholderia pseudomallei infection.

Authors:  Yahua Chen; Jocelyn Wong; Guang Wen Sun; Yichun Liu; Gek-Yen Gladys Tan; Yunn-Hwen Gan
Journal:  Infect Immun       Date:  2011-06-13       Impact factor: 3.441
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