Literature DB >> 12889089

Influence of monocyte chemoattractant protein 1 gene polymorphism on age at onset of sporadic Parkinson's disease.

Masataka Nishimura1, Sadako Kuno, Ikuko Mizuta, Mitsuhiro Ohta, Hirofumi Maruyama, Ryuji Kaji, Hideshi Kawakami.   

Abstract

We studied polymorphisms in the genes for monocyte chemoattractant protein 1 (MCP-1) and CC chemokine receptor (CCR)-2 in 171 Parkinson's disease (PD) patients and 340 controls. Although no associations were found in alleles or genotypes, MCP-1 -2518A/G genotype affected the age-at-onset of PD patients. This effect was also detected in a second PD group, suggesting a possible involvement of MCP-1 in PD. Copyright 2003 Movement Disorder Society

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Year:  2003        PMID： 12889089     DOI： 10.1002/mds.10462

Source DB:  PubMed          Journal:  Mov Disord        ISSN： 0885-3185            Impact factor:   10.338


  15 in total

1.  Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson's disease.

Authors:  R Pattarini; R J Smeyne; J I Morgan
Journal:  Neuroscience       Date:  2007-01-29       Impact factor: 3.590

Review 2.  Role of MCP-1 and CCR2 in alcohol neurotoxicity.

Authors:  Kai Zhang; Jia Luo
Journal:  Pharmacol Res       Date:  2018-11-22       Impact factor: 7.658

Review 3.  Role of α-synuclein in inducing innate and adaptive immunity in Parkinson disease.

Authors:  Heather E Allen Reish; David G Standaert
Journal:  J Parkinsons Dis       Date:  2015       Impact factor: 5.568

4.  Association of polymorphisms in the MCP-1 and CCR2 genes with the risk of Parkinson's disease.

Authors:  Yan Wang; Minhua Zhou; Yong Wang; Deqi Jiang; Xun Deng
Journal:  J Neural Transm (Vienna)       Date:  2019-08-30       Impact factor: 3.575

5.  MCP-1 and CCR2 gene polymorphisms in Parkinson's disease in a Han Chinese cohort.

Authors:  Liang Gao; Hongmei Tang; Kun Nie; Limin Wang; Jiehao Zhao; Rong Gan; Jing Huang; Shujun Feng; Ruiming Zhu; Zhenpeng Duan; Youwen Zhang; Xin Zhao; Yuhu Zhang; Lijuan Wang
Journal:  Neurol Sci       Date:  2014-11-05       Impact factor: 3.307

Review 6.  Correlation between MCP-1-2518A/G polymorphism and the risk of Alzheimer's disease.

Authors:  Yan Wang; Siyi Huang; Xiaoling Wu; Yong Wang; Deqi Jiang
Journal:  J Neural Transm (Vienna)       Date:  2018-10-03       Impact factor: 3.575

7.  Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis.

Authors:  Toru Nakazawa; Toshio Hisatomi; Chifuyu Nakazawa; Kosuke Noda; Kazuichi Maruyama; Haicheng She; Akihisa Matsubara; Shinsuke Miyahara; Shintaro Nakao; Yuqin Yin; Larry Benowitz; Ali Hafezi-Moghadam; Joan W Miller
Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-06       Impact factor: 11.205

Review 8.  Peripheral chemo-cytokine profiles in Alzheimer's and Parkinson's diseases.

Authors:  M Reale; N H Greig; M A Kamal
Journal:  Mini Rev Med Chem       Date:  2009-09       Impact factor: 3.862

9.  Neuronal MCP-1 mediates microglia recruitment and neurodegeneration induced by the mild impairment of oxidative metabolism.

Authors:  Guang Yang; Ya Meng; Wenxia Li; Yue Yong; Zhiqin Fan; Hanqing Ding; Youzhen Wei; Jia Luo; Zun-Ji Ke
Journal:  Brain Pathol       Date:  2010-11-03       Impact factor: 6.508

10.  Polymorphisms of chemokine and chemokine receptor genes in idiopathic immune-mediated posterior segment uveitis.

Authors:  Muhammad A Ahad; Tom Missotten; Atiyeh Abdallah; Penny A Lympany; Susan Lightman
Journal:  Mol Vis       Date:  2007-03-23       Impact factor: 2.367
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