Literature DB >> 1288426

The chemotherapy of rodent malaria. XLVII. Studies on pyronaridine and other Mannich base antimalarials.

W Peters1, B L Robinson.   

Abstract

The activities of Mannich base antimalarials, including pyronaridine, have been explored against drug-sensitive (Plasmodium berghei N) and chloroquine-resistant (Plasmodium yoelii NS) rodent malaria parasites in vivo. Lines of these parasites have been developed with resistance to pyronaridine, amodiaquine, or WR 228,258. The responses and patterns of cross-resistance of these lines to Mannich bases and other blood schizontocides are inconsistent. It is concluded that some Mannich bases may prove still to be of value inthe treatment of chloroquine-resistant Plasmodium falciparum infection.

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Year:  1992        PMID： 1288426     DOI： 10.1080/00034983.1992.11812694

Source DB:  PubMed          Journal:  Ann Trop Med Parasitol        ISSN： 0003-4983


  36 in total

Review 1.  Pharmacokinetic interactions of antimalarial agents.

Authors:  P T Giao; P J de Vries
Journal:  Clin Pharmacokinet       Date:  2001       Impact factor: 6.447

2.  In vivo antimalarial activity of the endophytic actinobacteria, Streptomyces SUK 10.

Authors:  Mohd Shukri Baba; Noraziah Mohamad Zin; Zainal Abidin Abu Hassan; Jalifah Latip; Florence Pethick; Iain S Hunter; RuAngelie Edrada-Ebel; Paul R Herron
Journal:  J Microbiol       Date:  2015-12-02       Impact factor: 3.422

3.  In vitro activities of pyronaridine, alone and in combination with other antimalarial drugs, against Plasmodium falciparum.

Authors:  P Ringwald; E C Eboumbou; J Bickii; L K Basco
Journal:  Antimicrob Agents Chemother       Date:  1999-06       Impact factor: 5.191

4.  Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs.

Authors:  Nadia Saïdani; Cyrille Y Botté; Michael Deligny; Anne-Laure Bonneau; Janette Reader; Ronald Lasselin; Goulven Merer; Alisson Niepceron; Fabien Brossier; Jean-Christophe Cintrat; Bernard Rousseau; Lyn-Marie Birkholtz; Marie-France Cesbron-Delauw; Jean-François Dubremetz; Corinne Mercier; Henri Vial; Roman Lopez; Eric Maréchal
Journal:  Antimicrob Agents Chemother       Date:  2014-02-18       Impact factor: 5.191

5.  Influence of formulation ratio of the plant components on the antimalarial properties of MAMA decoction.

Authors:  Samuel Akintunde Odediran; Anthony Adebolu Elujoba; Adeleke Clement Adebajo
Journal:  Parasitol Res       Date:  2014-05       Impact factor: 2.289

6.  In vitro and in vivo anti-malarial activity of Boerhavia elegans and Solanum surattense.

Authors:  Ali Ramazani; Sedigheh Zakeri; Soroush Sardari; Nastaran Khodakarim; Navid Dinparas Djadidt
Journal:  Malar J       Date:  2010-05-12       Impact factor: 2.979

7.  Antimalarial efficacy, cytotoxicity, and genotoxicity of methanolic stem bark extract from Hintonia latiflora in a Plasmodium yoelii yoelii lethal murine malaria model.

Authors:  Norma Rivera; Perla Y López; Marcela Rojas; Teresa I Fortoul; Diana Y Reynada; Alberto J Reyes; Ernesto Rivera; Hiram I Beltrán; Filiberto Malagón
Journal:  Parasitol Res       Date:  2014-02-19       Impact factor: 2.289

8.  Biological assay of a novel quinoxalinone with antimalarial efficacy on Plasmodium yoelii yoelii.

Authors:  Norma Rivera; Yovani Marrero Ponce; Vicente J Arán; Cecilia Martínez; Filiberto Malagón
Journal:  Parasitol Res       Date:  2013-01-22       Impact factor: 2.289

9.  Antimalarial, hematological, and antioxidant effects of methanolic extract of Terminalia avicennioides in Plasmodium berghei-infected mice.

Authors:  Akhere A Omonkhua; Mojisola C Cyril-Olutayo; Olusegun M Akanbi; Olayinka A Adebayo
Journal:  Parasitol Res       Date:  2013-07-20       Impact factor: 2.289

10.  Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model.

Authors:  D M Kiboi; B N Irungu; B Langat; S Wittlin; R Brun; J Chollet; O Abiodun; J K Nganga; V C S Nyambati; G M Rukunga; A Bell; A Nzila
Journal:  Exp Parasitol       Date:  2009-03-24       Impact factor: 2.011
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